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CAR-T cell therapy shows promise for treating autoimmune disorders but faces challenges like complex manufacturing and limited tissue penetration.

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

A new laser technique can precisely remove specific cell types in living animals without harming nearby cells.

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

PCR genotyping in cre-loxP mice can be inaccurate due to unintended gene deletions in non-target tissues.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

Combining certain treatments, including FOL005, may improve healing of difficult wounds.

Altering the keratin 17 gene in mice hair follicles caused temporary hair issues, but changes were minimal and short-lived.

Transcutaneous vaccination using nanoparticles can enhance immune responses and reduce basal cell carcinomas.

Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.

PEG and keratin scaffolds can effectively deliver protein drugs by controlling release based on pH levels.

A new engineered treatment shows promise in curing heart fibrosis.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

CTHRC1 is essential for healing and preventing heart rupture after a heart attack.

A new therapy for a skin blistering condition has not been developed yet.

Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

PRSS35 enzyme may help start skin tumors and could be a target for cancer treatment.

The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

CRISPR gene editing reduces harmful molecules in cells from Emery–Dreifuss Muscular Dystrophy patients.

The new treatment effectively heals drug-resistant bacteria-infected wounds.

The gene therapy showed significant wound healing and was safe for treating severe RDEB.

Trichohyalin is modified by enzymes to form strong structures in hair cells.