August 2025 in “Research Square (Research Square)” High TNF-α levels may increase hair loss risk after PRP therapy.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.
April 2024 in “Journal of cosmetic dermatology” Platelet-rich fibrin might be a promising treatment for hair loss, but more research is needed to confirm its effectiveness.
June 2020 in “Journal of Investigative Dermatology” FDA-cleared devices often fail to produce high-quality platelet-rich plasma consistently.
14 citations
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March 2023 in “Bioengineering” Standardized PRP is effective for tendinopathies, with most patients improving after one injection.
103 citations
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February 1972 in “Proceedings of the National Academy of Sciences” A unique enzyme in guinea pig hair follicles helps form protein cross-links in hair.
May 2022 in “Acta scientific dental sciences” Platelet concentrates are useful for tissue repair in medicine and dentistry, with L-PRF showing promising results in various treatments.
December 2023 in “American journal of medical genetics. Part A” A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.
1 citations
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April 2018 in “Journal of Investigative Dermatology” People respond differently to hair loss treatment with PRP because of individual differences in growth factors from platelets.
July 2022 in “Journal of Investigative Dermatology” High platelet numbers in PRP may not be essential for hair growth, and certain growth factors could negatively affect treatment outcomes for hair loss.
23 citations
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September 2020 in “Journal of Cosmetic Dermatology” Injectable Platelet-Rich Fibrin (I-PRF) showed positive results for treating hair loss, skin texture, wrinkles, and wounds.
8 citations
,
August 2020 in “Experimental dermatology” PRP therapy for alopecia shows inconsistent results due to natural variability in growth factor secretion by platelets.
7 citations
,
December 2018 in “Discoveries” Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.
52 citations
,
January 2003 in “Journal of Investigative Dermatology” Thrombospondin-1 is crucial for hair follicle regression and reduced blood vessel growth during the catagen phase.
1 citations
,
September 2024 in “Frontiers in Cell and Developmental Biology” PRF is better than PRP for endometrial repair.
88 citations
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December 2003 in “Journal of Biological Chemistry” Epiprofin helps cells grow in developing teeth, hair, and limbs.
1 citations
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March 2019 in “Suez Canal University Medical Journal (Print)” PRP speeds up healing with few side effects, but more research is needed to standardize its use.
May 2024 in “Clinical and experimental optometry”
September 2020 in “Medicina Moderna - Modern Medicine” A simple, cost-effective method to prepare high-quality PRP is suitable for smaller medical institutions.
16 citations
,
August 2023 in “Tissue Engineering and Regenerative Medicine”
April 2018 in “Journal of Investigative Dermatology” Fetuin A may increase collagen production and promote scarring.
7 citations
,
December 1970 in “Biochimica et Biophysica Acta (BBA) - Protein Structure”
11 citations
,
September 2005 in “International Wound Journal” A woman developed severe skin damage after using a blood thinner called low-molecular-weight heparin.
7 citations
,
August 2020 in “Journal of The American Academy of Dermatology” The document sets guidelines to standardize reporting of PRP clinical trials for better reproducibility and comparability.
1 citations
,
April 2016 in “Journal of The American Academy of Dermatology” A woman had a delayed allergic reaction to the blood thinner enoxaparin, treated with a steroid cream.
3 citations
,
May 2024 in “Diseases of the Colon & Rectum” Adding platelet-rich plasma does not improve healing of certain fistulas.
3 citations
,
October 2020 in “Journal of Transfusion Medicine” Platelet-rich plasma therapy is seen as a promising tissue repair method but lacks standardized protocols.
December 2025 in “International Journal of Surgery” GBP1 is a key target for treating Epstein-Barr virus-related kidney cancer, and finasteride may help.