234 citations
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April 2000 in “Gene” Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.
228 citations
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September 2012 in “Trends in Neurosciences” Nerves are crucial for the regeneration of various body parts in many animals.
218 citations
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January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
212 citations
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September 2015 in “Journal of Investigative Dermatology” The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
205 citations
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April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
176 citations
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May 2020 in “Dermatologic Therapy” COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.
173 citations
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January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
172 citations
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May 2018 in “Nature” Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
98 citations
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July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
81 citations
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July 2011 in “Lasers in Medical Science” The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.
78 citations
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May 1989 in “The Journal of Clinical Endocrinology & Metabolism” Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.
73 citations
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June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
67 citations
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November 2002 in “Journal of The American Academy of Dermatology” The document concludes that careful evaluation is key to diagnose and treat women with hair loss, with tests for thyroid, iron, and hormones as needed.
65 citations
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August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
65 citations
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September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
64 citations
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January 2004 in “American journal of clinical dermatology” Folliculitis is an inflammation of hair follicles that requires proper diagnosis and treatment based on the specific cause.
61 citations
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April 2012 in “British Journal of Dermatology” Caucasian women's hair appears thickest in their 20s, with perceived thinning after mid-30s due to both decreasing density and diameter.
55 citations
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November 2018 in “American journal of human genetics” Mutations in the LSS gene cause a rare type of hereditary hair loss.
55 citations
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September 2017 in “Expert Opinion on Drug Discovery” Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.
52 citations
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June 1981 in “International Journal of Dermatology” Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
46 citations
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December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
44 citations
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September 2012 in “Archives of Dermatology” Hair breakage may be an early sign of a hair loss condition called CCCA in African American women.
42 citations
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March 2018 in “PLOS Biology” Autophagy is important for human hair growth and health.
42 citations
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October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the KRT85 gene cause hair and nail problems.
41 citations
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October 2024 in “Nature Communications” A new wearable LED device helps heal chronic infected wounds at home.
39 citations
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March 2008 in “Journal of biological chemistry/The Journal of biological chemistry” GLI2 increases follistatin production in human skin cells.
36 citations
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August 2021 in “Nature Cell Biology” Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
36 citations
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January 2007 in “Archives of Histology and Cytology” Type IV collagen chains vary in different parts of human skin, with specific patterns linked to melanocytes.
33 citations
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February 2016 in “Journal of Experimental Botany” ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.
33 citations
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April 2012 in “British Journal of Dermatology” Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.