research The clinical development of a 5α-reductase inhibitor, finasteride
Finasteride effectively treats BPH, but needs more trials to understand potential.
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research Androgen Receptor Antagonists (Antiandrogens) Structure-Activity Relationships
Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
research Evaluation and treatment of male and female pattern hair loss
Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.
research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men
Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.
research The PDGF/PDGFR pathway as a drug target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
research What does the concept of the stem cell niche really mean today?
Stem cell niches support, regulate, and coordinate stem cell functions.
research S1-Leitlinie Post-COVID/Long-COVID
The guideline offers practical advice for diagnosing and treating Post-COVID/Long-COVID.
research Androgenetic Alopecia: An Evidence-Based Treatment Update
Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.
research S1 guideline for diagnostic evaluation in androgenetic alopecia in men, women and adolescents
Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.
research The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention
5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.
research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
research The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Finasteride
Finasteride effectively treats baldness but may cause sexual side effects.
research Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production
Testosterone's muscle-building effects do not require its conversion to DHT.
research Janus kinase inhibitors in dermatology: A systematic review
JAK inhibitors help with skin conditions but need more research on dosing and safety.
research Epidemiology and treatment modalities for the management of benign prostatic hyperplasia
More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.
research The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer
Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
research Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31
A new genetic region, 17q21.31, is linked to higher ovarian cancer risk.
research A Prospective, 1-Year Trial Using Saw Palmetto Versus Finasteride in the Treatment of Category III Prostatitis/Chronic Pelvic Pain Syndrome
Finasteride improves chronic pelvic pain, saw palmetto doesn't.
research Anti-cancer properties of olive oil secoiridoid phenols: a systematic review of in vivo studies
Olive oil compounds may help prevent cancer in animals, but human results are mixed.
research Androgenetic Alopecia
Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
research Male androgenetic alopecia
Hair loss in men treated best with early medication or transplant, new treatments researched.
research Endocrine control of benign prostatic hyperplasia
Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
research Diagnosis and management of the dermatologic manifestations of the polycystic ovary syndrome
The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.
research S1-Leitlinie Long-/Post-COVID
The guideline offers current advice for diagnosing and treating Long- and Post-COVID symptoms.
research Testosterone Supplementation for Aging-Associated Sarcopenia
Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
research The Effect of Finasteride on the Expression of Vascular Endothelial Growth Factor and Microvessel Density: A Possible Mechanism for Decreased Prostatic Bleeding in Treated Patients
Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.
research Androgenetic alopecia: An update
Minoxidil and finasteride effectively treat hair loss.
research Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing
Blocking β-catenin in skin cells improves hair growth during wound healing.
research Care of the transgender patient: the role of the gynecologist
Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.