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A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

Prepubertal girls have higher sex steroid levels than boys, possibly leading to earlier puberty.

Fox Fordyce disease might be more common in prepubertal girls than thought and can be managed with treatment.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

A man had four testicles, two of which were outside the scrotum and looked like fatty lumps.

A 10-year-old girl with Fox Fordyce disease improved with treatment, suggesting the disease can occur before puberty and might be underdiagnosed in young girls.

Testosterone and letrozole treatment speeds up puberty in boys with delayed development.

Testosterone significantly affects urination differences between male and female mice.

A 13-year-old boy with Cushing syndrome has high cortisol levels from a pituitary gland issue and underdeveloped sexual characteristics.

A six-year-old girl has early signs of puberty, needs no treatment, but requires regular check-ups for future health risks.

A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.

Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.

Anastrozole and cyproterone acetate treatment can help increase adult height in boys with testotoxicosis.

Early diagnosis of pseudopelade of Brocq in men is crucial to prevent permanent hair loss.

Most genital symptoms in prepubertal girls are normal or nontraumatic, not signs of abuse.

The dog's fertility was restored with antibiotics and finasteride treatment.

The new rodent model successfully mimics non-lean human PCOS symptoms.

A 15-year-old boy had a rare skin growth on his buttock.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Male accessory sex glands in rats rarely develop tumors and respond to hormones.

Puberty is driven by hormonal changes, mainly influenced by genetics, nutrition, and body fat.

Gene mutations can cause problems in male genital development.

Early puberty is more common in girls and African-American children, possibly due to nutrition, obesity, stress, and environmental factors, and is treated with hormone therapy.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Micro-CT helps identify suitable areas for surgical procedures based on blood vessel distribution in hypospadias-affected rats.

Testicular abnormalities in dogs should be treated to prevent complications like seminoma.

PCOS can cause unusual symptoms like late puberty and enlarged clitoris, making diagnosis difficult.

A 21-year-old had a rare developmental anomaly with a misplaced sebaceous gland in a hair follicle.