research An In Situ Chemotherapy Drug Combined with Immune Checkpoint Inhibitor for Chemoimmunotherapy
Combining specific nanoparticles with immune therapy significantly improves cancer treatment.
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research PHYTOCHEMICAL SCREENING AND IN-VITRO ANTI-FUNGAL ACTIVITY OF “TRIDAX PROCUMBENS L.
Tridax procumbens L. has compounds that can fight fungi.
research Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis
Midazolam impairs learning and memory by increasing neurosteroids through specific receptor activation.
research ANTIALOPECIA ACTIVITY EXPLORATION BY In-silico ANALYSIS OF BIOACTIVE COMPOUNDS FROM Sansevieria trifasciata PRAIN LEAVES THROUGH 5α-REDUCTASE INHIBITION
Methyl pyropheophorbide A from Sansevieria trifasciata leaves may help treat hair loss.
research Immediate and residual antifungal activity of compounds used for whole body and adjuvant topical therapy against Microsporum canis: an in vitro study
Enilconazole and lime sulfur work well for whole body treatment, while other products need frequent application for effective antifungal action.
research Standardization of Eclipta Alba by HPTLC, HPLC and AAS
The research confirmed that certain methods are reliable for standardizing Eclipta alba and ensuring its safety and quality in herbal products.
research Enhanced Skin Permeation and Controlled Release of β-Sitosterol Using Cubosomes Encrusted with Dissolving Microneedles for the Management of Alopecia
The new delivery system improved hair growth in alopecia treatment.
research The search for bioactive compounds in tropical plants to target hormone imbalance associated diseases
Piper cubeba and Aquilaria sinensis may help prevent or treat prostate issues by balancing hormones.
research Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum
The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
research Neurosteroids and epileptogenesis in the pilocarpine model: Evidence for a relationship between P450scc induction and length of the latent period
Neurosteroid production in the brain may delay seizure onset.
research Post-Exposure Syndromes as State-Space Trapping: A set-theoretic perspective on PSSD and the post-exposure family.
Post-exposure syndromes are persistent conditions caused by past exposures, needing unique interventions.
research Modulating mechanosensory afferent excitability by an atypical mG luR
A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research 128 Bimekizumab led to rapid & deep normalisation of molecular signatures associated with PASI sub-components, preceding clinical skin clearance
Bimekizumab quickly improves psoriasis symptoms and skin at the molecular level.
research 5. Novel anticonvulsant effects of supraphysiological doses of progesterone in hippocampal-kindled mice
High doses of progesterone can reduce seizures in mice.
research 42175 PASI improvement in the first 12 weeks from the Phase 3 VOYAGE 1, VOYAGE 2, ORION and ECLIPSE guselkumab clinical trials
Guselkumab significantly improves psoriasis symptoms within 12 weeks.
research Post-Exposure Syndromes as State-Space Trapping: A set-theoretic perspective on PSSD and the post-exposure family.
Post-Exposure Syndromes are persistent conditions caused by past exposures, needing unique interventions.
research Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting
P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
research Retiform Purpura Caused by the Use of Cocaine, That Was Probably Adulterated with Levamisole
Cocaine possibly mixed with levamisole caused a woman's skin condition and blood issues, which improved with treatment.
research Integrating systemic agents in clinic-based practice
Systemic agents like cyclosporine, methotrexate, and acitretin help manage psoriasis but have significant side effects.
research Tailoring Risperidone-Loaded Glycethosomal In Situ Gels Using Box–Behnken Design for Treatment of Schizophrenia-Induced Rats via Intranasal Route
The new nasal gel for schizophrenia improved drug absorption and brain effects in rats.
research A double blind, randomised, vehicle-controlled, safety and tolerance study of topical PSK 3841 solution at 5% administered twice daily over four weeks to healthy Caucasian males with androgenetic alopecia
research Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD
Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
research Psychoactive drugs and skin
Some psychoactive drugs can cause skin reactions, with carbamazepine having a higher risk, and stopping the drug and seeing a dermatologist is important.
research Palmitoylethanolamide Stimulation Induces Allopregnanolone Synthesis in C6 Cells and Primary Astrocytes: Involvement of Peroxisome-Proliferator Activated Receptor-α
PEA boosts allopregnanolone production and reduces oxidative stress in brain cells.
research Histologic Changes in the Skin of Hairless Mice Following Peeling With Salicylic Acid
Salicylic acid can safely exfoliate and regenerate skin without causing inflammation.
research Development and Invitro Evaluation of Solid Lipid Nano Particles Loaded Topical Gel Containing Combination of Drugs Used In The Better Therapy of Psoriasis
The new gel for psoriasis is effective, stable, and easy to apply.
research S2594 Autoimmune Hepatitis Due to Para-Aminobenzoic Acid
Para-aminobenzoic acid in hair supplements can cause autoimmune hepatitis.
research Understanding the formation mechanism of drug-polymer inclusion complex by structure elucidation and theoretical calculation
The research shows how certain drug molecules form stable structures with polymers, which could help create new drug forms.
research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors
The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.