March 2026 in “Frontiers in Medicine” Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
1 citations
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January 2020 in “Skin Appendage Disorders” Treatment with methotrexate and prednisolone led to complete hair regrowth and no relapse for 2 years.
218 citations
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April 2012 in “British Journal of Dermatology” Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.
Hair regrowth improved, but quality of life did not.
19 citations
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July 2022 in “PNAS Nexus” Similar treatments might work for different types of scarring hair loss.
November 2024 in “Journal of Investigative Dermatology” 
8 citations
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May 2025 in “Dermatology and Therapy” Local corticosteroids can help with alopecia areata, but hair loss often returns after stopping treatment.
2 citations
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January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” The most effective way to diagnose non-scarring hair loss is by transverse sectioning, and some cases, particularly in males with inflammation around hair follicles, might be curable.
February 2011 in “Annales de dermatologie et de vénéréologie” Tofacitinib shows promise for treating severe alopecia areata with good safety and effectiveness.
January 2025 in “Medical Research Archives” A new classification and scoring system is needed for alopecia areata to better assess severity.