May 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Clinicians need to better understand and treat Post-finasteride syndrome.
34 citations
,
December 2021 in “Journal of Clinical Medicine” Men with BPH should discuss potential sexual side effects with doctors before treatment, as some treatments can affect ejaculation.
44 citations
,
April 2015 in “PubMed” Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
3 citations
,
February 2019 in “Der Urologe” Medications for benign prostatic syndrome can cause cognitive issues and depression.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Gut bacteria imbalance may cause Post-Finasteride Syndrome symptoms.
May 2022 in “The Journal of Sexual Medicine” Finasteride is linked to sexual dysfunction, especially in younger men using it for hair loss.
1 citations
,
November 2022 in “Journal of the Academy of Consultation-Liaison Psychiatry” 8 citations
,
May 2016 in “Indian Journal of Pharmacology” Finasteride and dutasteride can cause severe, lasting side effects.
January 2003 in “Zhonghua shiyan waike zazhi” Androgen, especially DHT, is crucial for erectile function in rats by affecting specific brain neurons.
2 citations
,
August 2011 in “Cochrane Database of Systematic Reviews” January 2012 in “The Journal of Clinical Psychiatry”
December 2015 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.
66 citations
,
April 2017 in “International Journal of Andrology” Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.
April 2017 in “Reactions Weekly” Finasteride may cause weak ejaculation and reduced semen volume.
11 citations
,
April 2023 in “Annals of General Psychiatry” Serotonergic antidepressants can significantly increase the risk of erectile dysfunction and have a small risk of causing irreversible sexual dysfunction.
15 citations
,
March 2020 in “Anais Brasileiros De Dermatologia” Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
30 citations
,
February 2003 in “Annals of Neurology” Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
2 citations
,
February 2003 in “Annals of Neurology” Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
10 citations
,
May 2018 in “Neuropharmacology” Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
August 2024 in “medRxiv (Cold Spring Harbor Laboratory)” Finasteride has various adverse effects, including sexual dysfunction and mental health issues, which vary by age and gender.
11 citations
,
March 2019 in “Journal of The American Academy of Dermatology” Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.
July 2020 in “Vestnik urologii” The cause of post-finasteride syndrome is unclear and needs more research.
13 citations
,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
38 citations
,
January 1991 in “International Journal of Dermatology” Men over 35 with hair improvement felt better psychologically, while younger men felt better even without hair improvement.
32 citations
,
March 2019 in “Climacteric” Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.
May 2003 in “Reactions Weekly”
73 citations
,
July 2013 in “The Journal of Sexual Medicine” Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.
1 citations
,
December 2016 in “The Journal of Sexual Medicine” Many different biological, psychological, and social factors can cause sexual dysfunction in American women.
June 2024 in “International journal of impotence research” The author had undisclosed conflicts of interest related to the original article on post-finasteride syndrome.
January 2017 in “Indian journal of sexually transmitted diseases and AIDS” Finasteride, a hair loss drug, can cause sexual side effects like erectile dysfunction in 2.1%-3.8% of users, but these usually go away with time or if the drug is stopped. Despite this, its impact on sexual function is minimal for most men.