research Green Technologies in the Generic Pharmaceutical Industry
Green technologies can make the pharmaceutical industry more sustainable by reducing waste.
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research Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research OVERCOMING THE BARRIERS TO EFFECTIVE DRUG DELIVERY TO THE BRAIN
New methods are being developed to improve drug delivery to the brain.
research Phytotherapeutic Interventions using Rodent Models of Hair Loss: Current Research and Future Strategy
Natural products show promise for new hair loss treatments.
research 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction
Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
research Why Do Promising Therapies Stall in Development and How Can We Move Them Forward?
Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.
research Scalp Dysesthesia
Antidepressants may improve or resolve scalp dysesthesia in most patients.
research Cognitive and mood side effects of lower urinary tract medication
Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
research Effects of digital health education intervention on stress, anxiety and depression of patients with polycystic ovarian syndrome: study protocol for a single blinded randomized controlled trial
Digital health education may reduce stress, anxiety, and depression in PCOS patients.
research Influence of age and of testosterone on the response of male rats to parachlorophenylalanine
PCPA induces hypersexual behavior in male rats regardless of age or castration status.
research Early post-natal neuroactive steroid manipulation modulates ondansetron effects on initial periods of alcohol consumption in rats
Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.
research TELECONSULTA EM INSUFICIÊNCIA CARDÍACA: REVISÃO DE ESCOPO
Passiflora incarnata may help with anxiety and sleep issues but has side effects; teleconsultation for heart failure can improve quality of life; increased screen time for children during the pandemic led to more clinical complaints; older and severely affected COVID-19 patients are more likely to have long-term symptoms.
research Details always tell a big story: Importance of physical symptoms in evaluation of secondary causes of depression
Physical symptoms in depression can reveal underlying medical conditions.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Evolving treatment paradigms in dermatology: Insights from emerging and repurposed therapies
New and repurposed treatments are improving outcomes in dermatology.
research Pharmacological Control of Reproduction in the Dog and Cat
Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.
research Hair care product use among pregnant women of color: protocol for a feasibility educational intervention
Educational efforts can reduce harmful chemical exposure from hair products in pregnant Women of Color.
research Оптимизация подходов консервативной терапии доброкачественной гиперплазии предстательной железы ингибиторами 5-альфаредуктазы. Клинико-морфологическое исследование
5-alpha-reductase inhibitors can effectively treat benign prostatic hyperplasia.
research Will it ever grow back? The psychosocial impacts of alopecia
Alopecia, a hair loss issue, needs both medical and psychological treatments due to the limited effectiveness of drugs alone.
research Phytochemicals and novel delivery systems in alopecia management: An integrative review
Combining herbal medicines with modern delivery systems may improve alopecia treatment.
research Pharmacologically altered Androgens, Brain Activation and Response Inhibition in a Stop-Signal Task in Male Heavy Drinkers
Lower DHT and higher testosterone levels increase brain activation but don't change behavior in heavy drinkers.
research Pharmacological management of polycystic ovary syndrome
PCOS treatment should be personalized, using birth control pills or metformin for symptoms, with lifestyle changes being essential.
research Pharmacological Management of Pattern Hair Loss
The best treatments for slowing down pattern hair loss are minoxidil and finasteride, with some other drugs and hair transplantation also used.
research Recent advances in the treatment of psoriasis
New treatments for psoriasis have improved effectiveness and may reduce long-term side effects when combined with standard therapies.
research Safety update: psychiatric and sexual adverse effects with finasteride
Finasteride can cause depression, suicidal thoughts, and lasting psychiatric and sexual issues.
research Targeted Therapy– and Chemotherapy-Associated Skin Toxicities: Systematic Review and Meta-Analysis
Minocycline reduces acne rash, pyridoxine lowers hand-foot syndrome risk, and scalp cooling lessens hair loss from cancer treatments.
research Psychiatric and sexual dysfunction warnings strengthened for finasteride and dutasteride
Finasteride and dutasteride now have stronger warnings for psychiatric and sexual side effects.
research Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition
Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.
research Double Dosing
Taking the same medication under different brand names caused harmful side effects.
research The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder
Finasteride reduces opioid use and withdrawal symptoms in animals.