research A computational approach to mechanistic and predictive toxicology of pesticides
Pesticides can cause reproductive and adrenal health issues.
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research Alopecia associated with agomelatine use: a case report
Stopping the antidepressant agomelatine improved hair loss in a patient.
research Eosinophilia associated with clozapine – A case report
A patient's allergic reaction to clozapine resolved without stopping the medication, showing the importance of blood monitoring.
research American College of Veterinary Behaviorists 2003 Scientific Session Abstracts
Transdermal fluoxetine is less effective in cats, clomipramine may help with feline alopecia, younger dogs often start fights, dietary changes can reduce cribbing in horses, negative aggression tests in shelter dogs predict good behavior, many older cats show cognitive issues, and fluoxetine or paroxetine can improve canine anxiety.
research Hair Loss as a Side Effect of Quetiapine: A Clinical Case Report
Quetiapine may cause hair loss.
research 187 Protective Effect of DA-9401 on Acute use of Finasteride on Sprague–Dawley Rats
DA-9401 protects against hair loss, improves organ function, and prevents infertility caused by finasteride.
research Social isolation alters GABAA receptors plasticity and function: effect of voluntary consumption of ethanol
Social isolation changes brain receptors and makes ethanol more impactful.
research Pharmacovigilance in Pediatric Patients with Epilepsy Using Antiepileptic Drugs
Most children with epilepsy on antiepileptic drugs experience side effects, especially those on multiple drugs, but these drugs help reduce seizures.
research Expert Opinion: Migraine, Psychiatric Comorbidities, and Treatment
People with migraines often have mental health conditions, and treatment should be personalized to address both issues safely.
research P.1.g.012 Neurocognition in patients with bipolar type I disorder in remission: relation between vitamin B12 and folic acid
research Lifestyle Drugs
The article concludes that a balance is needed between individual healthcare needs and societal resources when it comes to lifestyle drugs, with a call for compassionate policy application.
research Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output
Lower allopregnanolone levels increase stress-related dopamine release in the brain.
research Cyproterone Acetate in the Treatment of Sexual Disorders: Pharmacological Base and Clinical Experience
Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.
research Valproate‐associated hair abnormalities: Pathophysiology and management strategies
Valproate can cause hair problems, but there are ways to manage them.
research TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network
TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.
research New steps forward in the neuroactive steroid field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research How Should You Use the Lab to Monitor Patients Taking a Mood Stabilizer
Patients on mood stabilizers need regular health checks, but many aren't monitored properly.
research Rethinking serotonin’s role in mental health
Serotonin's role in mental health is complex and not fully understood, affecting treatment effectiveness.
research 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives
Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
research Light therapy as a treatment for sexual dysfunction; focus on testosterone levels
research The Pharma Market as Reflected by Patents
The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.
research Progesterone Promotes Anti-Anxiety/Depressant-like Behavior and Trophic Actions of BDNF in the Hippocampus of Female Nuclear Progesterone Receptor, but Not 5α-Reductase, Knockout Mice
Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.
research Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats
Finasteride may reduce depression and anxiety in female rats and improve brain connectivity.
research Pharmacological therapy of benign prostatic hyperplasia/lower urinary tract symptoms: an overview for the practising clinician
Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.
research Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids
A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.
research Polymorphism
Different crystal forms of drugs can change their effectiveness.
research Androgens and Antiandrogens
Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
research Possible involvement of 5α-reduced neurosteroids in adrenergic and serotonergic stimulation of GFAP gene expression in rat C6 glioma cells
5α-reduced neurosteroids may help regulate glial cell differentiation.
research Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson’s Disease
NDP-MSH protects brain cells and reduces inflammation in Parkinson's disease by activating MC1R and involving Tregs.
research Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.