research A New Look at the 5?-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
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research Cytostatics and immunosuppressive drugs
Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
research FeCl3-catalysed C-N coupling reaction between cyclic ethers and heterocyclic amines
Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.
research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research 265 Modulation of disease-central cytokine pathways with TAK-279, a highly selective oral tyrosine kinase 2 (TYK2) inhibitor, defines clinical response in patients with psoriasis
TAK-279 effectively reduces psoriasis symptoms and is safe.
research Cluster Headache-Acute and Prophylactic Therapy
Sumatriptan injections, high-flow oxygen, and verapamil effectively treat cluster headaches.
research Further Studies of Effects of Finasteride on Mood and Suicidal Risk
Finasteride may affect mood and increase suicidal risk.
research Towards the Development of AgoKirs: New Pharmacological Activators to Study Kir2.x Channel and Target Cardiac Disease
New compounds may help treat heart disease by activating specific potassium channels.
research Associations of schizophrenia with the activities of the HPA and HPG axes and their interactions characterized by hair-based biomarkers
research Pharmacology of antiandrogens
Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
research Finasteride/spironolactone
research Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK
Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
research Finasteride inhibits epinephrine synthesis in humans: implication for sexual dysfunction
Finasteride may cause sexual dysfunction by reducing epinephrine levels.
research Clinically-Relevant Chemotherapy Interactions with Complementary and Alternative Medicines in Patients with Cancer
Some herbal medicines can interfere with chemotherapy, affecting treatment and causing side effects.
research Effects of local and systemic medications on eye health: Adverse reactions
Medications can cause eye problems, so regular eye check-ups are important.
research Steroid 5α-reductase inhibition by polymethoxyflavones
Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.
research The therapeutic use of topical contact sensitizers in benign dermatoses
Topical contact sensitizers can treat certain skin conditions by changing the immune response.
research Emerging medications
research Selective Sensing of Darolutamide and Thalidomide in Pharmaceutical Preparations and in Spiked Biofluids
A new, efficient method has been developed to detect darolutamide and thalidomide, drugs used for certain hair loss and prostate cancer treatments, in pharmaceuticals and body fluids.
research Valproate Induced Hair Loss and Curly Hair in Bipolar Disorder
Valproate can cause both hair loss and curly hair in bipolar disorder patients.
research Nanocarriers for melatonin delivery
Nanocarriers make melatonin more effective and reduce side effects.
research Why Do Promising Therapies Stall in Development and How Can We Move Them Forward?
Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.
research An overview of current strategies and future prospects in drug repurposing in tuberculosis
Drug repurposing offers promising strategies to improve tuberculosis treatment despite challenges.
research Hair cortisol in drug-naïve first-episode individuals with psychosis
First-episode psychosis patients have higher hair cortisol levels, indicating early stress response issues.
research Gonadal Suppressive and Cross‐Sex Hormone Therapy for Gender Dysphoria in Adolescents and Adults
Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.
research Finasteride
research PD29-07 DRUGS ASSOCIATED THE MOST WITH MALE-FACTOR INFERTILITY: ASSESSMENT OF THE 2010-2020 FOOD AND DRUG ADMINISTRATION (FDA) PHARMACOVIGILANCE DATABASE
Finasteride and testosterone are the drugs most linked to male infertility, but many other potential drugs may be under-reported.
research The Drug Reboot: Finding New Life in Old Formulations
Repurposing existing drugs can quickly and cheaply find new treatments for diseases.
research A Concise Review on Biological Activity of Tridax procumbens Linn
Tridax procumbens has medicinal properties like healing, pain relief, and infection control.
research Pharmacology and Potential Use of Cyproterone Acetate
Cyproterone Acetate effectively treats androgen-related conditions and is used in prostate cancer therapy and hormone therapy for transgender women.