18 citations
,
January 2013 in “Postepy Dermatologii I Alergologii” Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.
3 citations
,
September 2020 in “Journal of developmental and behavioral pediatrics/Journal of developmental & behavioral pediatrics” The document discusses a young boy with autism and early puberty but does not provide a conclusion on managing his behavior.
173 citations
,
November 2004 in “Seminars in Reproductive Medicine” Adrenarche increases adrenal androgens around age 6, affecting hair growth and development.
January 2017 in “Springer eBooks” Understanding genes and hormones is crucial for managing male puberty and sex development disorders.
1 citations
,
July 2001 in “Pediatrics in review” The girl has a hormonal imbalance causing increased hair growth and other male characteristics.
11 citations
,
October 2002 in “The Journal of Clinical Endocrinology & Metabolism” Enzyme activities do not cause early pubic hair in these girls.
21 citations
,
December 2015 in “Development Growth & Differentiation” DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.
9 citations
,
August 1986 in “Archives of Pediatrics and Adolescent Medicine” Familial sexual precocity in girls may be more common than previously thought.
July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.
10 citations
,
September 2007 in “Pediatrics in Review” Gynecomastia and premature thelarche often resolve naturally but need evaluation to rule out serious issues.
September 2024 in “Pediatrics in Review” Parental support and gender-affirming care are crucial for the mental health of transgender adolescents.
July 2024 in “Reproductive health of woman” Girls conceived via assisted reproductive technologies show early puberty signs and larger ovaries.
26 citations
,
March 1981 in “Clinical Endocrinology” Oestrogen does not affect adrenal androgen levels in children and adolescents.
11 citations
,
September 1990 in “Clinical Endocrinology” Girls with prepubertal simple hypertrichosis have higher dihydrotestosterone (DHT) levels.
11 citations
,
January 2011 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” Adolescents and young adults with Prader-Willi syndrome show a range of sexual interests and behaviors.
26 citations
,
November 1993 in “Progress in Neuro-psychopharmacology & Biological Psychiatry” Treatment during development affects hormone balance and sexual behavior in male rats.
October 1984 in “Kidney international” The patient had complex urinary tract issues and ambiguous genitalia, with physical features suggesting a hormonal imbalance.
January 2018 in “Elsevier eBooks” 5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.
February 2010 in “ePrints Soton (University of Southampton)” Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
45 citations
,
April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
June 2025 in “V F Snegirev Archives of Obstetrics and Gynecology” A six-year-old girl has early signs of puberty, needs no treatment, but requires regular check-ups for future health risks.
September 2020 in “Journal of Health, Medicine and Nursing” A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.
77 citations
,
September 1983 in “Acta Paediatrica” Dexamethasone effectively normalizes elevated steroid levels in girls with premature adrenarche.
December 1981 in “Pediatric Research” 17 citations
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February 2014 in “Pediatric Research” July 2020 in “Endocrine practice” A 13-year-old boy with Cushing syndrome has high cortisol levels from a pituitary gland issue and underdeveloped sexual characteristics.
July 2001 in “Pediatrics in review” The girl's increased hair growth and other symptoms were due to a hormone-secreting ovarian tumor, which was successfully treated with surgery.
111 citations
,
May 2001 in “Human reproduction update” Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
September 2023 in “Journal of The American Academy of Dermatology” Adolescents with hair loss show different hormone levels by sex and often have related metabolic issues.
December 2022 in “Journal of Pharmaceutical Negative Results” Late onset of first period and irregular development of sexual traits in teenage girls can lead to poorer reproductive health.