29 citations
,
February 2019 in “Environment international” Higher early lead exposure is linked to delayed puberty in girls.
192 citations
,
January 1976 in “The Journal of Clinical Endocrinology & Metabolism” Androgen levels increase with puberty and are linked to sexual hair development.
19 citations
,
March 2004 in “The Journal of Clinical Endocrinology & Metabolism” Testosterone and letrozole treatment speeds up puberty in boys with delayed development.
37 citations
,
June 2011 in “Pediatrics in Review” Puberty is driven by hormonal changes, mainly influenced by genetics, nutrition, and body fat.
3 citations
,
June 2017 in “Deep Blue (University of Michigan)” Early exposure to fluoride, lead, and certain nutrients affects puberty differently in boys and girls.
2 citations
,
April 2022 in “Annales d Endocrinologie” Recombinant gonadotropins improve future fertility in CHH patients.
2 citations
,
January 2000 in “Pediatrics in review” Early sexual development in children, especially girls, can be treated with hormone therapy to improve adult height and requires support for the child and family.
11 citations
,
July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
15 citations
,
May 2010 in “Pediatrics in Review” Delayed puberty often runs in families, can affect growth, and may need hormone treatment.
173 citations
,
May 2001 in “Human reproduction update” Oestrogens are key for bone growth during puberty in both boys and girls.
22 citations
,
March 2019 in “Environmental health” Higher fluoride levels may delay puberty in boys.
January 2016 in “Springer eBooks” Pubertal acne is linked to hormonal changes, affects quality of life, and is treated similarly to adult acne.
13 citations
,
January 2019 in “Endocrine journal” Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.
1 citations
,
May 2018 in “Clinical chemistry” The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.
5 citations
,
May 2023 in “Science of the total environment” PFAS exposure in adolescence may delay puberty in females.
40 citations
,
July 2016 in “Pediatrics in review” Puberty involves complex hormonal changes, varies by gender and ethnicity, and requires careful monitoring for abnormalities.
8 citations
,
January 2022 in “BMC Biology” Environmental factors affect reproductive traits by altering the SRD5A1 gene.
5 citations
,
July 2019 in “Nutrients” Low selenium intake may delay puberty in boys but not in girls.
284 citations
,
February 2008 in “Pediatrics” Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
166 citations
,
October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
17 citations
,
February 2020 in “Journal of Pediatric and Adolescent Gynecology” Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.
5 citations
,
February 2019 in “Neuroscience letters” Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
2 citations
,
September 2017 in “Archives of Medical Science” Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
2 citations
,
April 2021 in “PLoS ONE” Rural Bangladeshi girls mature later than peers in other low and middle-income countries due to poor nutrition and socioeconomic conditions.
49 citations
,
January 2010 in “International Journal of Pediatric Endocrinology” The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.
31 citations
,
January 2018 in “Pediatric annals” Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
19 citations
,
December 2021 in “Endocrine Reviews” There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
11 citations
,
April 2013 in “Homo” Darker skin in 10-year-old girls may be an early sign of puberty.
1 citations
,
October 2022 in “Adolescent Health, Medicine and Therapeutics” Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.
16 citations
,
January 2017 in “Asian journal of andrology/Asian Journal of Andrology” Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.