7 citations
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June 2006 in “Pediatrics in Review” Most genital symptoms in prepubertal girls are normal or nontraumatic, not signs of abuse.
13 citations
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May 1996 in “Archives of Disease in Childhood” Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.
July 2015 in “NEJM Journal Watch” Diagnosing and treating PCOS in young people is difficult.
10 citations
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December 2019 in “in Vivo” Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.
3 citations
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May 2019 in “Ginekologia Polska” Adolescents with abnormal uterine bleeding often have polycystic ovarian syndrome and insulin resistance.
5 citations
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December 2018 in “Frontiers in Endocrinology” Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.
November 2022 in “Journal of the Endocrine Society” A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
14 citations
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September 2014 in “Journal of Pediatric and Adolescent Gynecology” Irregular menstrual cycles in teenagers are linked to a higher risk of polycystic ovary syndrome and metabolic syndrome.
January 2019 in “Springer eBooks” Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.
3 citations
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December 1997 in “Pediatric Clinics of North America” Pediatricians should advise sexually active teens on safe sex and STD prevention, and discuss contraceptive options and their side effects.
October 2025 in “Journal of the Endocrine Society” Early physical exams are crucial for timely Klinefelter syndrome diagnosis.
January 2019 in “Oncogen” Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
26 citations
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November 1993 in “Progress in Neuro-psychopharmacology & Biological Psychiatry” Treatment during development affects hormone balance and sexual behavior in male rats.
3 citations
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October 1993 in “Endocrinology” August 2025 in “Geburtshilfe und Frauenheilkunde” Adolescents with PCOS need tailored diagnosis and support, including lifestyle advice and managing related health issues.
1 citations
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April 2015 in “The FASEB Journal” Blocking androgens in male rats increased estrogen and made them more active.
July 2020 in “Research Square (Research Square)” Obesity and certain hormone levels can lead to advanced bone age in young girls with early breast development.
65 citations
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October 2008 in “Journal of Neuroendocrinology”
9 citations
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October 2017 in “Translational pediatrics” Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.
October 1995 in “Pediatric Research” 5 citations
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July 1987 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” The treatment temporarily improved symptoms of hyperandrogenism in adolescents.
January 2011 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” Hyperthyroidism can hide signs of high androgen levels in females.
January 2001 in “Cambridge University Press eBooks” Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.
9 citations
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January 1997 in “Endocrine Journal” Gonadal biopsy is the best method to diagnose gonadal dysgenesis.
8 citations
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September 2020 in “Journal of adolescent health” Gender-affirming care for youth remained essential during the COVID-19 pandemic, with telemedicine playing a key role.
2 citations
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December 2022 in “Journal of Clinical Medicine” Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.
26 citations
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September 2005 in “Pharmacology Biochemistry and Behavior” 5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.
34 citations
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June 2010 in “Archives of Disease in Childhood” Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.
86 citations
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March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
14 citations
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January 2012 in “Endocrine development” The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.