research Developmental origin of polycystic ovary syndrome - a hypothesis
The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.
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research TNF superfamily in skin appendage development
TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
research Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction
High levels of androgens during early development may cause PCOS-like symptoms.
research Depletion of S100A4+ stromal cells results in abnormal nipple development and nursing failure
Lack of certain cells causes abnormal nipple development and nursing failure.
research The effect of gonadoliberin analog treatment in precocious puberty on polycystic ovarian syndrome prevalence in adulthood
Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.
research The laboratory in the multidisciplinary diagnosis of differences or disorders of sex development (DSD)
Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
research The clinical development of a 5α-reductase inhibitor, finasteride
Finasteride effectively treats BPH, but needs more trials to understand potential.
research Development and homeostasis of the sebaceous gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
research Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne
Genetic variations affecting skin structure play a key role in severe acne.
research Development and characterization of minoxidil-loaded liposomal system for delivery to pilosebaceous units
Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.
research A Case of Familial Male-limited Precocious Puberty with a Novel Mutation
A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.
research Development and Characterization of Film Forming Spray of 5% Minoxidil for Baldness Due to Androgenetic Alopecia
A 5% minoxidil spray could effectively treat male baldness with fewer side effects and better patient comfort.
research 46, XY Disorder of Sexual Development with Ambiguous Female External Genitalia: A Case Report
A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.
research Development of cosmeceutical cream for dermatitis and acne vulgaris
The cream effectively treats acne and dermatitis without causing irritation.
research Distinct stem cells contribute to mammary gland development and maintenance
Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
research Gonadotropin releasing hormone agonist (nafarelin) test to differentiate gonadotropin deficiency from constitutionally delayed puberty in teen-age boys--a clinical research center study.
The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.
research Recent discoveries and developments of androgen receptor based therapy for prostate cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research The tendency towards the development of psychosexual disorders in androgenetic alopecia according to the different stages of hair loss: a cross-sectional study
More hair loss leads to higher risk of psychosexual disorders, especially in women.
research Role of 5α-dihydrotestosterone in testicular development of gilthead seabream following finasteride administration
DHT affects testicular development and regulates spermatogenesis in some fish.
research Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
research Wnt target gene Ascl4 is dispensable for skin appendage development
The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.
research PROBLEMS OF CREATING SCIENTIFIC IDEAS ABOUT WORLD DEVELOPMENT
Continuous research and innovative strategies are essential for sustainable development.
research Gynecological and dermatological aspects of diagnostics of polycystic ovary syndrome from puberty to menopause
PCOS is common, affects fertility, and requires personalized treatment to manage symptoms and health risks.
research Polymorphisms in Genes Involved in Steroidogenesis in the Development of Severe Acne
Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.
research Steroid Hormones of Reproduction and Sexual Development
Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
research Effects of in Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in the Male Rat
Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
research Health-related quality of life questionnaire for polycystic ovary syndrome (PCOSQ-50): development and psychometric properties
The PCOSQ-50 is a valid and reliable questionnaire for measuring quality of life in Iranian women with PCOS.
research Hormone-induced aberrations in electromagnetic adhesion signaling as a developmental factor of androgenetic alopecia
Hormones cause hair loss by affecting cell growth and weakening cell attraction.
research Is Prenatal Sex Hormone Balance a Risk Factor for the Development of Hidradenitis Suppurativa
Lower 2D:4D finger ratios in HS patients suggest prenatal hormone influence on the disease.
research Neonatal allopregnanolone or finasteride administration modifies hippocampal K+ Cl− co-transporter expression during early development in male rats
Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.