November 2023 in “Australasian journal of dermatology” Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.
March 2022 in “IntechOpen eBooks” Botulinum Neurotoxin-A can treat acne, oily skin, rosacea, hair loss, prevent scars, relieve nerve pain, reduce excessive sweating, and manage psoriasis, but more trials are needed to confirm its effectiveness.
January 2018 in “Dermatology Online Journal” Alopecia areata is hard to treat, but new targeted therapies show promise.
318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
186 citations
,
February 2015 in “Frontiers in Neuroscience” Testosterone affects brain behavior in complex and varied ways.
141 citations
,
May 2007 in “Cancer Research” CD34 is crucial for skin tumor development in mice.
125 citations
,
May 2010 in “Pediatric dermatology” Systemic treatment is necessary for tinea capitis in children, with griseofulvin preferred for Microsporum infections.
91 citations
,
May 2023 in “Journal of Cutaneous Medicine and Surgery” Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.
87 citations
,
December 2015 in “Cochrane library” No single treatment is clearly effective for central serous chorioretinopathy.
78 citations
,
May 2019 in “Frontiers in Cellular and Infection Microbiology” DPK-060 in poloxamer gel effectively treats skin infections, but nanocarriers don't enhance its efficacy.
78 citations
,
January 2013 in “Dermatology Online Journal” Hidradenitis suppurativa is linked to various diseases like obesity, depression, arthritis, and Crohn's disease, but often occurs alone.
58 citations
,
February 2013 in “Journal of Biological Chemistry” LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.
57 citations
,
November 2024 in “Aggregate” Smart hydrogels can improve diabetic wound healing by adapting to wound conditions and providing controlled treatment.
50 citations
,
January 2007 in “PubMed” Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.
44 citations
,
August 2014 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.
43 citations
,
July 2023 in “Pharmaceuticals” Caffeine can boost health, prevent diseases, and improve performance, with new methods enhancing its benefits.
36 citations
,
August 2022 in “Molecular Therapy — Nucleic Acids” Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
34 citations
,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
30 citations
,
November 2024 in “ACS Materials Au” Microneedles are promising for disease monitoring and drug delivery due to their minimal invasiveness and versatility.
25 citations
,
January 2024 in “Journal of Lipids” Cubosomes improve drug delivery for skin and eye diseases by enhancing adhesion, retention, and release.
25 citations
,
February 2023 in “Aesthetic Surgery Journal” Photobiomodulation is safe for skin rejuvenation, even for those with a cancer history.
23 citations
,
January 2017 in “Journal of Functional Biomaterials” Biomaterials can help reduce skin scarring and improve wound healing.
22 citations
,
September 2017 in “Skin appendage disorders” Ruxolitinib helped a man regrow his beard after years of hair loss.
21 citations
,
June 2023 in “Journal of Nanobiotechnology” Engineered extracellular vesicles could improve CRISPR/Cas delivery, making gene editing safer and more effective.
20 citations
,
September 2015 in “Pediatric Annals” PCOS in teen girls should be managed with lifestyle changes and sometimes medication to improve symptoms and health.
19 citations
,
January 2023 in “Frontiers in Bioengineering and Biotechnology” MSC-sEVs may effectively treat chronic non-healing wounds.
19 citations
,
December 2021 in “Endocrine Reviews” There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
19 citations
,
February 2021 in “Journal of Clinical Investigation” More research is needed on the health effects of hormone therapy for transgender and nonbinary people.
17 citations
,
January 2025 in “Journal of Nanobiotechnology” Bacterial extracellular vesicles could revolutionize regenerative medicine but need safety improvements.
16 citations
,
April 2025 in “Journal of the American Academy of Dermatology” Photobiomodulation is safe and effective for treating certain conditions like nerve pain and hair loss.