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TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Increased energy use in Pik3r1-related insulin resistance isn't due to Ucp1 thermogenesis.

Agouti and AGRP affect pigmentation and obesity, with implications for metabolic disorders.

Dermatopathia pigmentosa reticularis causes skin discoloration, hair loss, and nail problems.

SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.

A mutation in the hairless gene speeds up severe itchy skin in mice on a special diet.

ERK activation spreads between cells in mouse skin, linked to cell division and influenced by TPA and EGF receptors.

PGF_2α receptors in human eyelids are found in specific parts of hair follicles, explaining eyelash changes with glaucoma treatment.

Progesterone reduces anxiety without needing progesterone receptors.

PRC2 is not essential for hair follicle stem cell maintenance or hair growth.

PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.

High-throughput LC-MS screening is effective for finding new autotaxin inhibitors for asthma treatment.

PDGF signaling is crucial for cell development, wound healing, and fluid regulation in the body.

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

PRF lysates reduce inflammation in cancer cells and boost immune response in healthy oral cells.

Lack of FPR2 slows hair growth by affecting hair cell activity.

Polycomb Repressive Complex 1 is crucial for keeping stem cells stable and maintaining healthy adult tissues.

Blocking TRPV3 may help treat itch in dry skin conditions.

Triphenylphosphine oxide can increase oil production and reduce inflammation in skin cells without affecting TRPM5.

CP-690,550 significantly reduced itching in patients with moderate-to-severe plaque psoriasis.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

TRα and CRABPII genes change their activity levels during goat fetal skin development.

PTHrP is higher in certain dog tumors and may act as a local growth factor.

Activating cannabinoid receptor 1 may help manage psoriasis by reducing certain keratins.

The mineralocorticoid receptor temporarily affects mouse skin development, but the glucocorticoid receptor has a more lasting impact.

Neuroactive steroids affect cocaine's rewarding effects through the ς₁ receptor.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Hair dye ingredient PPD can cause severe allergic reactions, including facial swelling.

Pentoxifylline effectively improves pretibial pruritic papular dermatitis.