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Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs

research Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs

11 citations , October 2019 in “Cancers”

Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.

research NFIC promotes the vitality and osteogenic differentiation of rat dental follicle cells

11 citations , August 2019 in “Journal of Molecular Histology”

NFIC helps rat dental cells grow and turn into bone-like cells.

research Deletion analysis of AGD1 reveals domains crucial for its plasma membrane recruitment and function in root hair polarity

11 citations , June 2017 in “Journal of cell science”

AGD1's PH domain is essential for its role in root hair growth and polarity.

research Metabolic dysfunction in female mice with disruption of 5α-reductase 1

11 citations , January 2017 in “Journal of Endocrinology/Journal of endocrinology”

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

research Localization of the rabies virus antigen in Merkel cells in the follicle-sinus complexes of muzzle skins of rabid dogs

11 citations , September 2016 in “Journal of virological methods”

Rabies virus was found in specific skin cells of rabid dogs' muzzles, suggesting these cells could help diagnose rabies.

Androgen Receptor Activation Integrates Complex Transcriptional Effects in Osteoblasts, Involving the Growth Factors TGF-β and IGF-I, and Transcription Factor C/EBPδ

research Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ

11 citations , July 2015 in “Gene”

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor

research Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor

11 citations , May 2015 in “Stem Cells Translational Medicine”

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

Effects of Food-Derived Collagen Peptides on the Expression of Keratin and Keratin-Associated Protein Genes in Mouse Skin

research Effects of Food-Derived Collagen Peptides on the Expression of Keratin and Keratin-Associated Protein Genes in the Mouse Skin

11 citations , January 2015 in “Skin pharmacology and physiology”

Eating collagen peptides may help with skin and hair growth.

A Spontaneous Deletion Within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype

research A Spontaneous Deletion within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype

11 citations , December 2014 in “The American journal of pathology”

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

The Possible Implication of the S250C Variant of the Autoimmune Regulator Protein in a Patient with Autoimmunity and Immunodeficiency: In Silico Analysis Suggests a Molecular Pathogenic Mechanism for the Variant

research The possible implication of the S250C variant of the autoimmune regulator protein in a patient with autoimmunity and immunodeficiency: in silico analysis suggests a molecular pathogenic mechanism for the variant

11 citations , July 2014 in “Gene”

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

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