research High-Precision On-line Total Phenolic Compounds Analysis Oxidized by Folin Ciocalteu: Application to Ziziphus Jujuba Extract
A new method accurately measures phenolic compounds in Ziziphus Jujuba extract quickly and efficiently.
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research Individual Human Hair Keratin Rapidly Extracted Through the Advanced Oxidation Process and Their Hemostatic and Wound Healing Evaluations
The new method extracts keratin from hair faster and better, and the resulting product improves blood clotting and wound healing, with potential for personalized treatments.
research Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism
Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.
research Inhibition of the pro-oxidant effects of benoxaprofen on poiymorpbonuclear leucocytes by retinol acetate in vitro
Retinol acetate can reduce the harmful effects of the drug benoxaprofen on white blood cells.
research Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research The Role and Mechanism of Nanozymes in Burn Wound Healing
Nanozymes help heal burn wounds by fighting bacteria, reducing inflammation, and promoting blood vessel growth.
research Self-adaptive nanozymes with enhanced multi-enzyme activities for sequential multimodal therapy of drug-resistant bacteria-infected wounds
The new treatment effectively heals drug-resistant bacteria-infected wounds.
research Corrigendum to “Nitric oxide synergizes Minoxidil delivered by transdermal hyaluronic acid liposomes for multimodal androgenetic-alopecia therapy” [Bioact. Mater. 32 (2024) 190–205]
![Patent Evaluation: Hexahydrobenzo[f]quinolines as 5α-Reductase Inhibitors](/images/research/1634373b-f615-46c7-a157-21394e3366be/small/21095.jpg)
research Patent Evaluation: Hexahydrobenzo[f]quinolines as 5α-reductase inhibitors
Hexahydrobenzo[f]quinolines are effective at blocking the enzyme 5α-reductase.
research DiZyme: The Ultimate Resource for Nanozyme Multiple Catalytic Activity Prediction
DiZyme accurately predicts nanozyme activities to aid in discovering new applications.
research Antipsychotic-Like Properties of 5-α-Reductase Inhibitors
research Keyora Integrated Nutritional Modulation of the Redox–NO–Androgen Axis in Male Endocrine, Reproductive, and Metabolic Disorders
Nutritional interventions can help restore balance in male health by targeting oxidative stress and hormonal issues.
research Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism
Red light exposure slows aging in mice by improving fat metabolism.
research Skin of color repigmentation after phenol-croton oil chemical peel
Skin of color can spontaneously repigment after a phenol-croton oil chemical peel.
research Effects of Solvent System and Storage Condition on Chemical Stability of 5(alpha)-Reductase Inhibitor Compounds in Tectona grandis L.f. Leaf Extracts
Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.
research A wearable and stretchable dual-wavelength LED device for home care of chronic infected wounds
A new wearable LED device helps heal chronic infected wounds at home.
research Kaempferol Rhamnosides from Geranium sibiricum as Aldose Reductase Inhibitors and Their Content by HPLC Analysis
Geranium sibiricum may help manage diabetic complications by inhibiting a key enzyme.
research Sulfation of minoxidil by liver sulfotransferase
Liver enzyme helps minoxidil work better for blood vessel relaxation.
research Auxin signaling gets oxidative to promote root hair growth
Auxin promotes root hair growth through oxidative processes involving reactive oxygen species.
research Multicolor Cell Barcoding Technology for Long-Term Surveillance of Epithelial Regeneration in Zebrafish
Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
research Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism
Red light exposure can slow aging in mice by improving fat metabolism.
research Age-induced hair greying - the multiple effects of oxidative stress
Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
research Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids
A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.
research Determination Method for Steroid 5α-Reductase Activity Using Liquid Chromatography/Atmospheric Pressure Chemical Ionization–Mass Spectrometry
A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.
research Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization
Reactive oxygen species (ROS) influence hair growth by causing DNA damage, cell death, and changes in immune cells.
research Iron Metabolism of the Skin: Recycling versus Release
Iron is crucial for skin health, with specific proteins recycling it to support skin functions and prevent its release.
research Carbobenzoxy-capped Phe-Lys(BODIPY TMR-X-acyloxymethyl ketone(QSY7)
Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.
research Comparison of Activities Dependent on Glutathione S-Transferase and Cytochrome P-450 IA1 in Cultured Keratinocytes and Reconstructed Epidermal Models
Reconstructed skin models are useful for studying how skin processes certain chemicals.
research Cloning, expression and characterization of rhesus macaque types 1 and 2 5alpha-Reductase: evidence for mechanism-Based inhibition by finasteride
Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
research In vitro evaluation of changes of hair fibers subjected to oxidation-reductive straighteners associated with dyeing
Straightening and dyeing damage hair structure.