research Long-lasting Antimicrobial Effect Achieved via Immobilization of Antimicrobial Agents on Hair Shaft
Treated hair can fight dandruff and odor even after several washes.
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research Chitosan microparticles for sustaining the topical delivery of minoxidil sulphate
Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.
research Two Different Mutations in the Same Codon of a Type II Hair Keratin (hHb6) in Patients with Monilethrix
Mutations in the hHb6 gene cause the hair disorder monilethrix.
research Quercetin rescues dihydrotestosterone-treated human dermal papilla cells via SHP2/AKT signaling to suppress autophagy and apoptosis
research Mechanism of action of minoxidil sulfate-induced vasodilation: a role for increased K+ permeability.
Minoxidil sulfate relaxes muscle by increasing potassium flow, making it a unique muscle relaxer.
research Identification of the sulfotransferase iso-enzyme primarily responsible for the bio-activation of topical minoxidil.
A specific enzyme that activates the hair growth medication minoxidil when applied to the skin was identified.
research Pharmacophore and Atom Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research Monilethrix: Mutational Hotspot in the Helix Termination Motif of the Human Hair Basic Keratin 6
Monilethrix severity varies and may be influenced by other genetic or environmental factors.
research Sulfation of minoxidil by human liver phenol sulfotransferase
Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
research Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy
The substance DMC helps get rid of aging cells by triggering a process that causes cell death, which could treat age-related diseases.
research The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: Nude mouse as an animal model
Aging and sun damage do not increase the skin's absorption of certain sunscreens and drugs.
research Isoxazole 9 (ISX9), a small molecule targeting Axin, activates Wnt/β‐catenin signalling and promotes hair regrowth
Isoxazole 9 (ISX9) may help regrow hair by activating certain cell signals.
research XMU-MP-1 induces growth arrest in a model human mini-organ and antagonises cell cycle-dependent paclitaxel cytotoxicity
XMU-MP-1 stops cell growth in a human mini-organ and reduces the effectiveness of the chemotherapy drug paclitaxel.
research Development and Validation of Spectrophotometric Method for Determination of Finasteride in Pharmaceutical Formulation Using 1,2-Naphthoquine-4-sulfonate (NQS)
New method accurately measures finasteride in medicine using NQS.
research Design, synthesis and anti-tumor evaluation of novel thiohydantoin congeners as androgen receptor antagonists with in vivo study.
A new compound, 3a, effectively fights prostate cancer better than finasteride.
research Rosemary oil-based microemulsion co-delivering quercetin and adenosine promotes hair regeneration in androgenetic alopecia via multiple actions
research Mitochondrial deoxyguanosine kinase depletion induced ROS causes melanocyte stem cell exhaustion and hair greying
Lack of a certain enzyme causes hair to grey early by damaging stem cells, but an antioxidant can help prevent this.
research Smoothened antagonists for hair inhibition
Two new compounds were found to effectively reduce hair growth in mice.
research Biocompatible exosomes derived from Pinctada martensii mucus for therapeutic melanin regulation via α-MSH/NF-κB/MITF pathway
Exosomes from Pinctada martensii mucus can safely reduce melanin production, offering a new treatment for skin pigment issues.
research Potentiometric determination of minoxidil in topical use pharmaceutical samples
The conclusion cannot be provided as the document content is not available.
research Characterisation of Myotonic Dystrophy type I cell models and drug evaluation by a cell- based quantification platform.
Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.
research QuantAnts machines discover biomarkers for RAS signaling activation and design sgRNAs for CRISPR to target complex CD9, CD34, and CD74.
The QuantAnts machines can find cancer markers and create CRISPR targets for them.
research Molecular docking simulation studies on potent butyrylcholinesterase inhibitors obtained from microbial transformation of dihydrotestosterone
Metabolite 7 is a strong inhibitor for Alzheimer's disease management.
research Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK
Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.
research Determinação de minoxidil em formulações farmacêuticas usando permanganometria
A simple and fast method accurately measures minoxidil in pharmaceuticals.
research A Combination Therapy for Androgenic Alopecia Based on Quercetin and Zinc/Copper Dual-Doped Mesoporous Silica Nanocomposite Microneedle Patch
A new patch that releases quercetin, copper, and zinc ions under the skin can effectively treat hair loss by promoting hair follicle regeneration.
research FC054 The liver monoxygenase system in patients with alopecia
Alopecia patients have a less active liver monoxygenase system, which can be treated with photochemotherapy and system inducers.
research 1372 Modulation of YBX1 phosphorylation determines epidermal stem cell function
Changing YBX1 protein activity affects skin stem cell function and aging.
research Transdermal delivery of mixnoxidil with block copolymer nanoparticles
Smaller nanoparticles improve minoxidil delivery through hair follicles.
research Fast determination of minoxidil by photometric flow titration
A quick method to measure minoxidil using a light-based titration technique was developed.