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Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

The microneedle patch with quercetin, zinc, and copper effectively promotes hair regrowth for androgenic alopecia.

MK-386 lowers DHT in blood and skin but not in semen.

Low ERCC3 gene activity is linked to non-pigmented hair growth.

Keratin structure changes during keratinization, but the exact model remains uncertain.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

Knockout mice showed anemia and hair loss, suggesting other ways exist for iron absorption.

Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Genetic variations may affect how well finasteride works for BPH patients.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

REV7 is crucial for genome stability and cancer treatment, making it a potential target for therapy.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

Finasteride may affect PNMT, causing side effects.

Different enzymes are active in different parts of developing mouse organs.

A new mutation in the KRT86 gene was found to cause the hair disorder monilethrix in a Han family.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.

The compounds tested could potentially treat hair loss and alopecia.

FLCN helps control iron levels in cells.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

The microneedle patch with CuxO nanozymes effectively promotes hair growth for treating hair loss.

Low PON1 levels may indicate and predict the severity of hair loss.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.