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Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

Transglutaminase-3 is often reduced in esophageal cancer.

Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

RC48 shows promise for treating certain advanced cancers, but more research is needed.

An 8-year-old girl has a rare, irreversible hair loss condition caused by a genetic mutation.

Genetic variants at 20p11 increase baldness risk in Chinese Han people.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

A rare type of skin cancer with mucosal involvement was partially treated but eventually relapsed.

A child with skin and tooth symptoms was found to have a genetic mutation causing cardiocutaneous syndrome, leading to heart problems.

Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

A genetic mutation linked to longer life and less disease was found in the Amish, and a drug is being developed to replicate these benefits.

Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Some children in Malaysia with symptoms have either profound or partial biotinidase deficiency, and early testing and treatment are important.

Consider Sertoli-Leydig cell tumors in Peutz-Jeghers syndrome patients with adnexal masses.

Epidermolytic ichthyosis can be inherited in a semidominant way with mild symptoms in carriers.

Deleting TNFα gene reduces skin cancer risk in certain mice.

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

Understanding genes and mutations can lead to new treatments for hair loss disorders.

Lack of functional CYLD in mice leads to early aging and cancer.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

qPCR is effective for quickly diagnosing fungal infections in horses.

Mutations in the CYP21A2 gene are not a major factor in causing PCOS.

HSD11b1 affects skin nerves and increases non-histaminergic itch.

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

Mice with human skin protein K8 had more skin problems and cancer.

Early involution in Hirosaki hairless rats' mammary glands is linked to a unique modification of STAT5A.

A specific gene mutation causes monilethrix in this family, and minoxidil treatment improves hair condition.

The HCR gene contributes to psoriasis risk.