January 2022 in “Stem cell biology and regenerative medicine” New hair can grow at wound sites, which could help improve treatments for hair loss and wound healing.
112 citations
,
July 2008 in “Dermatologic Therapy” Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.
14 citations
,
April 2017 in “American Journal of Transplantation” Skin problems from transplant drugs are common and need careful management in organ transplant patients.
September 2017 in “Springer eBooks” PRP injection therapy shows promise for treating hair loss, increasing hair count and thickness with minimal side effects.
65 citations
,
September 2014 in “BMC genomics” Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.
7 citations
,
August 2020 in “Majalah Farmasetika” A herbal hair tonic with 2.5% green tea extract is most effective for hair growth.
June 2023 in “MPI (Media Pharmaceutica Indonesiana)” A hair tonic made from kale leaves is effective for hair growth and meets Indonesian standards.
1 citations
,
February 2017 in “Journal of pharmacology & clinical research” The herbal hair gel with Eclipta alba and Lippia nodiflora extracts was more effective at growing hair than the control gel and minoxidil.
June 2024 in “Pharmacon Jurnal Farmasi Indonesia” A 1:3 ratio of virgin coconut oil to candlenut oil is best for promoting hair growth.
1 citations
,
April 2023 in “Journal of Animal Science and Biotechnology” Melatonin helps grow more secondary hair follicles in young goats, improving cashmere production.
1 citations
,
February 2023 in “International Journal of Molecular Sciences” Melatonin improves cashmere goat hair quality by increasing follicles and reducing skin aging.
1540 citations
,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
418 citations
,
September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
359 citations
,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
344 citations
,
June 2006 in “American Journal Of Pathology” Human hair follicles can provide stem cells for regenerative medicine.
329 citations
,
January 1997 in “Journal of the American Academy of Dermatology” Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.
319 citations
,
November 2005 in “Proceedings of the National Academy of Sciences” Hair follicle stem cells can help repair damaged nerves.
308 citations
,
September 2010 in “Nucleic acids research” Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
305 citations
,
December 2000 in “The EMBO Journal” Inhibiting Bmp signaling disrupts hair growth and differentiation.
272 citations
,
September 2001 in “Journal of Biological Chemistry” Human hair keratins were cataloged, showing their roles in hair differentiation stages.
235 citations
,
July 1999 in “Journal of biological chemistry/The Journal of biological chemistry” Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
226 citations
,
January 2006 in “International review of cytology” Keratin-associated proteins are crucial for hair strength and structure.
166 citations
,
July 1999 in “American Journal Of Pathology” The hairless (hr) gene is essential for normal hair follicle function and its mutation leads to hair loss.
149 citations
,
September 2017 in “Pharmaceutics” Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
130 citations
,
December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
128 citations
,
August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
119 citations
,
November 2016 in “American journal of human genetics” Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.
108 citations
,
July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
100 citations
,
September 1999 in “British Journal of Dermatology” The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
98 citations
,
June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” A cluster of sulfur-rich hair protein genes was found on chromosome 17.