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research 057 Single cell RNA and TCR sequencing reveals hyperexpansion of T cell clones and novel regulatory mechanisms of CD8+ T cells in murine alopcecia areata skin and draining lymph nodes

July 2024 in “Journal of Investigative Dermatology”

CD8+ T cells expand significantly in alopecia areata, suggesting new treatment targets.

K15 And Id3 Expression In Intact And Regenerating Adult Vibrissae Rodent Hair Follicles

research K15 & Id3 expression in intact and regenerating adult vibrissae rodent hair follicles

January 2009

K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.

research Steroidogenesis of the testis – new genes and pathways

70 citations , April 2014 in “Annales d'endocrinologie”

New genes and pathways are important for testosterone production and male sexual development.

research The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development

16 citations , March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

research A novel missense mutation (C622G) in the zinc‐finger domain of the human hairless gene associated with congenital atrichia with papular lesions

47 citations , April 2000 in “Experimental Dermatology”

A new gene mutation causes a rare type of hair loss.

research Functional Analysis of VDR Gene Mutation R343H in A Child with Vitamin D-Resistant Rickets with Alopecia

6 citations , November 2017 in “Scientific reports”

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

ROS-Responsive Hydrogel-Delivered miR-665 Targets STAT3 to Alleviate Inflammation and Promote Hair Follicle Regeneration in Alopecia Areata

research ROS-responsive hydrogel-delivered miR-665 targets STAT3 to alleviate inflammation and promote hair follicle regeneration in alopecia areata

February 2026 in “Journal of Nanobiotechnology”

A new treatment using a special gel with miR-665 reduces inflammation and helps hair regrow in alopecia areata.

research Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing

99 citations , October 2008 in “Journal of Investigative Dermatology”

Mutations in the ST14 gene cause skin and hair issues by disrupting important protein processing.

research Faculty Opinions recommendation of Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation.

June 2003 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

GLABRA2 represses root hair formation by inhibiting a specific gene.

research MAD2B acts as a negative regulatory partner of TCF4 on proliferation in human dermal papilla cells

8 citations , September 2017 in “Scientific Reports”

MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.

research The Phenotypic and Genotypic Spectra of Ichthyosis With Confetti Plus Novel Genetic Variation in the 3′ End ofKRT10i>

22 citations , September 2014 in “JAMA dermatology”

Ichthyosis with confetti is a genetic skin disorder with consistent ectodermal malformations and various KRT10 gene mutations.

research Expression of caspase-14 and keratin-19 in the human epidermis and appendages during fetal skin development
19 citations , February 2013 in “Archives of Dermatological Research”

research The retarded hair growth ( rhg ) mutation in mice is an allele of ornithine aminotransferase ( Oat )
9 citations , January 2014 in “Molecular Genetics and Metabolism Reports”

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

research LIGA R and D and prototyping[Lithography, Electroforming, and Assembly]
July 1999 in “Journal of the American Academy of Dermatology”

research A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity
91 citations , May 2005 in “The Journal of Clinical Endocrinology & Metabolism”

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

research Glypican-1, -4 and 6 Participate in the Hair Follicle Stem Cell Differentiation via Specific Interactions with BMP2R, Fz7 and Patched 1
October 2024 in “SPIRE - Sciences Po Institutional REpository”

research The HOXC13-controlled expression of early hair keratin genes in the human hair follicle does not involve TALE proteins MEIS and PREP as cofactors
18 citations , November 2005 in “Archives of Dermatological Research”

research IL-17 inhibition: is it the long-awaited savior for alopecia areata?
28 citations , March 2018 in “Archives of Dermatological Research”

research 583 Induction of type 17 collagen decreases ultraviolet b-induced cellular senescence in human htert/ker-ct keratinocytes
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Increasing type 17 collagen reduces aging signs in skin cells caused by UV light.

research Both Retinoic Acid Receptors α (RARα) and γ (RARγ) Are Able to Initiate Mouse Upper-Lip Skin Glandular Metaplasia
10 citations , August 1998 in “Journal of Investigative Dermatology”

research Generating mouse models of degenerative diseases using Cre/lox-mediated in vivo mosaic cell ablation
20 citations , May 2011 in “Journal of Clinical Investigation”

The study created a mouse model to mimic degenerative diseases for testing tissue repair and new therapies.

research Promotion of Skin Carcinogenesis by Dimethylarsinic Acid in Keratin (K6)/ODCi> Transgenic Mice
48 citations , June 2000 in “Japanese Journal of Cancer Research”

Dimethylarsinic acid speeds up skin tumor growth in certain mice.

research Insertional mutation of the hairless locus on mouse Chromosome 14
19 citations , November 1993 in “Mammalian Genome”

A gene mutation in mice causes permanent hair loss and skin issues.

research Steroid 17β-hydroxysteroid dehydrogenase deficiency in man: An inherited form of male pseudohermaphroditism
46 citations , December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology”

Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.

research A novel EDA variant that causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family
August 2025 in “BMC Pregnancy and Childbirth”

A new EDA gene variant causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family.

research Two Opposing Faces of Retinoic Acid: Induction of Stemness or Induction of Differentiation Depending on Cell-Type
41 citations , October 2019 in “Biomolecules”

Retinoic acid can either maintain stem cells or make them specialize, depending on the cell type.

research PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis
26 citations , August 2019 in “Stem Cell Research & Therapy”

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

research Lamellar ichthyosis with pseudoexon activation in the transglutaminase 1 gene
10 citations , March 2015 in “Journal of dermatology”

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.

research BMP4 and nuclear laminC orchestrate a expression of AHF/Trichohyalin molecule, a key modulator of keratin intermediate filaments in the hair follicle
January 2007

research The possible implication of the S250C variant of the autoimmune regulator protein in a patient with autoimmunity and immunodeficiency: in silico analysis suggests a molecular pathogenic mechanism for the variant
11 citations , July 2014 in “Gene”

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

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