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Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Multiphoton microscopy effectively images mouse skin layers and structures.

CRISPR-Cas9 can successfully edit genes in large mammals like Cashmere goats.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Dog skin with hair loss, when transplanted to mice, regrew hair, suggesting the hair loss cause is likely body-wide, not skin-specific.

Vitamin C deficiency changes gene expression, affecting skin and hair health.

Disrupted stem cell signals in hairpoor mice cause hair loss.

The UHS promoter is specific to mouse hair follicles.

Some people have a genetic variation that makes them less effective at breaking down drugs.

Mutating the gmds gene in zebrafish increases hair cell numbers and regeneration.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

miR-29 is a key factor that accelerates aging.

Matriptase-2 helps control iron levels by suppressing hepcidin, and its deficiency can cause iron-deficiency anemia.

Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.

Activating Tgr5 may help treat hair loss and bone loss.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.

The animal models successfully simulated dry eye related to sex steroid deficiency.

Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.

Mouse and human keratin 16 can both form filaments, with differences likely due to the tail domain, not the helical domain.

Dkk4 protein is necessary for the proper development and arrangement of hair follicles.

The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.

The mouse models are effective for testing new hair loss treatments.

GRF is not safe for tubal occlusion.