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Tyrosine Kinase 2 Inhibition Ameliorates the Phenotype of Lesional Alopecia Areata Scalp Skin Ex Vivo, and Reverses the Induction of Human Alopecia Areata in a Humanized Mouse Model

research 014 Tyrosine Kinase 2 Inhibition Ameliorates the Phenotype of Lesional Alopecia Areata Scalp Skin Ex Vivo, and Reverses the Induction of Human Alopecia Areata in a Humanized Mouse Model

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

TYK2 inhibition may help treat alopecia areata by promoting hair growth and reducing immune response.

research BC05 Technological and clinical demonstration of a skin ageing analysis prototype

June 2023 in “British Journal of Dermatology”

The prototype for analyzing skin aging works technically and clinically.

research Vitamin D Receptor: New Assignments for an Already Busy Receptor

510 citations , August 2006 in “Endocrinology”

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

research Androgen receptor-mediated gene activation in prostate cancer cells

1 citations , September 2010 in “UEF eRepo (University of Eastern Finland)”

Androgen receptors help prostate cancer cells grow and resist drugs.

Expression Patterns of Glial Cell Line-Derived Neurotrophic Factor, Neurturin, Their Cognate Receptors GFRα-1, GFRα-2, and Common Signal Transduction Element c-Ret in Human Skin Hair Follicles

research Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles

18 citations , January 2008 in “Journal of The American Academy of Dermatology”

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

research Corrections to “Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells”

June 2007 in “Journal of Investigative Dermatology”

research Identification of drug-specific public TCR driving severe cutaneous adverse reactions

88 citations , August 2019 in “Nature communications”

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

research Devices and genomic therapies

May 2023 in “Elsevier eBooks”

The document's conclusion cannot be provided because the document is not readable or understandable.

Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model

research Virtual Bioequivalence Assessment of Ritlecitinib Capsules with Incorporation of Observed Clinical Variability Using a Physiologically Based Pharmacokinetic Model

15 citations , January 2024 in “The AAPS Journal”

50-mg ritlecitinib capsules are bioequivalent to 100-mg capsules.

research Efficient Silencing of Androgen Receptor Gene via UTR-Targeting siRNAs for Androgenetic Alopecia Therapy

September 2025 in “Journal of Medicinal Chemistry”

AR-27 E-Chol siRNA can effectively regrow hair by reducing androgen receptor gene activity.

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