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July 1998 in “Journal of Investigative Dermatology” The authors confirmed that β-estradiol inhibits hair growth in mice when used at the correct concentration.
14 citations
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April 2022 in “Functional & Integrative Genomics” Key molecular interactions were identified that help understand hair follicle development in cashmere goats.
148 citations
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May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
25 citations
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September 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.
May 2005 in “Cancer Research” Melanoma cells lose their ability to form tumors when placed in a zebrafish embryo environment.
December 2021 in “Molecular genetics and genomics” Cats with abnormal hair had DSG4 gene changes causing hair problems.
37 citations
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December 2003 in “Reproductive Toxicology” The assay effectively detects hormonal activity of certain chemicals.
December 2007 in “한국미용학회지” The complex oriental medicine extract was as effective as minoxidil for hair regrowth in mice without adverse effects.
11 citations
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May 1995 in “The journal of investigative dermatology/Journal of investigative dermatology” October 2019 in “Asian College of Neuropsychopharmacology” January 2009 in “한방재활의학과학회지” Saengbal-eum-2 promotes hair growth and reduces inflammation in mice.
131 citations
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March 2004 in “The American journal of pathology” Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
4 citations
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February 2024 in “Poultry Science” miR-140-y helps control feather growth in geese by affecting the Wnt signaling pathway.
231 citations
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October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
14 citations
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September 2001 in “Archives of Dermatological Research” Blocking hair follicle development stops key gene signals needed for hair growth in mice.
26 citations
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June 2003 in “PubMed” Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.
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December 2009 in “Neuroscience” GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.
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September 2016 in “World Rabbit Science” High wool density in Rex rabbits is linked to specific gene activity affecting hair follicle development.
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January 2022 in “Animal Reproduction” Using rodents for research shows that health problems in the womb can cause diseases later in life.
December 2024 in “European journal of medical research” January 1993 in “Claves de razón práctica” ROR2 is crucial for hair follicle stem cell maintenance and self-renewal.
December 2024 in “Veterinary Sciences” Key genes and pathways improve wool quality in Zhexi Angora rabbits.
June 2005 in “Journal of Investigative Dermatology” A bull with a gene mutation was asymptomatic, synthetic retinoids cause hair loss, and new therapeutic targets were identified for skin diseases.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
380 citations
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March 2000 in “Proceedings of the National Academy of Sciences” Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.
November 2019 in “Synapse” Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
1 citations
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September 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.
April 2023 in “Journal of Investigative Dermatology” Human TMEM2 does not break down hyaluronan but helps control its metabolism.
164 citations
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December 1984 in “Proceedings of the National Academy of Sciences” TCDD reduces EGF receptor activity and causes various developmental changes in animals.
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August 2023 in “Development Genes and Evolution”