91 citations
,
August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
87 citations
,
August 2017 in “Scientific Reports” The nanofiber scaffolds improved skin wound healing by supporting cell growth and tissue repair.
87 citations
,
July 2012 in “Expert Review of Clinical Immunology” Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
84 citations
,
December 2017 in “EMBO Reports” Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
83 citations
,
November 2002 in “British Journal of Dermatology” Low iron levels are not directly linked to chronic hair loss and iron supplements may not help.
83 citations
,
May 1999 in “International Journal of Dermatology” Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.
82 citations
,
May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
75 citations
,
September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
75 citations
,
October 2010 in “Mammalian genome” Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.
75 citations
,
January 1995 in “American journal of primatology” Vervet monkeys show physical changes like hair loss and scrotal color changes due to stress or nutrition issues.
71 citations
,
September 2007 in “Cancer” Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.
70 citations
,
October 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
70 citations
,
March 2008 in “Mechanisms of Ageing and Development” Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
67 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.
65 citations
,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
62 citations
,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
59 citations
,
November 2010 in “Circulation Research” Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
59 citations
,
September 2007 in “Biochemical and Biophysical Research Communications” The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
55 citations
,
October 2003 in “Dermatologic Clinics” Different hair care practices and conditions affect African American hair and scalp health, requiring specialized knowledge for treatment.
47 citations
,
December 2019 in “Frontiers in immunology” A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
46 citations
,
June 2018 in “American Journal of Clinical Dermatology” Hair loss is common in lupus patients and can be permanent or reversible, depending on the type, with various treatments available.
43 citations
,
February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
43 citations
,
October 2002 in “International Journal of Cosmetic Science” All three shampoos reduced dandruff and hair loss, but ketoconazole and piroctone olamine also made hair thicker.
42 citations
,
April 2021 in “Journal of clinical pharmacology” Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
42 citations
,
November 2019 in “Frontiers in Endocrinology” The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
42 citations
,
January 1998 in “BioDrugs” Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.
41 citations
,
September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
40 citations
,
June 2013 in “Scientific Reports” A gene variant in KRT71 causes the curly fur in Selkirk Rex cats.
40 citations
,
May 1999 in “Journal of The European Academy of Dermatology and Venereology” Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.
39 citations
,
November 1987 in “Clinica Chimica Acta” Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.