research Stimulation of Hair Growth by Small Molecules that Activate Autophagy
Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
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research The logic of follicular unit transplantation
The document concludes that follicular unit transplantation offers more natural results and better graft survival than older hair transplant methods.
research Oestrogen functions in skin and skin appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells
Overactive sonic hedgehog signaling worsens uterine scarring by reducing cell recycling.
research Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research Follicular Unit Extraction
FUE provides minimal scarring and quick recovery in hair transplantation, and surgeons not using it may lag in technology.
research Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research Birt–Hogg–Dubé syndrome: from gene discovery to molecularly targeted therapies
New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
research Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
research Premature aging syndromes: From patients to mechanism
Studying premature aging syndromes helps understand human aging and suggests potential treatments.
research Disruption of tubular Flcn expression as a mouse model for renal tumor induction
Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.
research Tissue Expansion and Serial Excision in Scar Revision
Both tissue expansion and serial excision are effective for scar revision in the head and neck area.
research Drug repositioning using in silico compound profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Sesn2/AMPK/mTOR signaling mediates balance between survival and apoptosis in sensory hair cells under stress
Sesn2 protects inner ear hair cells from damage by regulating certain cell survival pathways.
research Alopecia areata incognita: True or false?
The authors suggest that a new type of hair loss exists, which is different from alopecia areata.
research Engineered Hair Follicle Mesenchymal Stem Cells Overexpressing Controlled-Release Insulin Reverse Hyperglycemia in Mice with Type l Diabetes
Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
research Cutaneous Toxicities From Transplantation-Related Medications
Skin problems from transplant drugs are common and need careful management in organ transplant patients.
research Sodium Metabisulfite: Effects on Ionic Currents and Excitotoxicity
Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.
research mTORC1 activity negatively regulates human hair follicle growth and pigmentation
High mTORC1 activity slows hair growth and causes it to lose color.
research The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.AktWT mice
Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
research The effect of long‐chain monoenes on prostaglandin E2 synthesis by rat skin
High levels of certain fats in rapeseed oil can reduce the skin's ability to produce prostaglandin E2 and cause hair loss and skin issues in rats.
research Shedding Light on the Effects of Calorie Restriction and Its Mimetics on Skin Biology
Eating fewer calories may slow skin aging and improve skin health through various biological changes.
research Acne keloidalis nuchae in renal transplant patients receiving tacrolimus and sirolimus
Renal transplant patients on tacrolimus and sirolimus may develop acne keloidalis nuchae.
research Ectopic hair on the glans penis
A man grew hair on his penis, which is not common, and needed surgery to remove it.
research Folliculin Deficient Renal Cancer Cells Show Higher Radiosensitivity through Autophagic Cell Death
Kidney cancer cells without folliculin are more sensitive to radiation due to increased self-eating cell death.
research Predominance of CD27-PD-1- Effector Memory T Cells Re-Expressing CD45RA Characterizes Treatment-Resistant Severe Alopecia Areata
CD8+ T cells re-expressing CD45RA may predict treatment resistance in severe alopecia areata.
research Adverse Reactions to Biologic Medications Used in Allergy and Immunology Diseases
Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.
research Microsporum gypseum isolated from a feline case of dermatophytosis
A cat had a rare fungal infection caused by Microsporum gypseum.
research Alopecia and Amphetamine Use-Reply
Amphetamines may not directly cause hair loss, as the type of thinning seen with their use differs from severe alopecia.