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Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Enzyme purified and characterized for minoxidil sulphation in rat liver.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

QSOX enzymes help form protein bonds in cells, especially in tissues with high secretory activity.

SASH1 gene mutations are linked to various inherited skin pigmentation disorders.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

5α-reductase inhibitors may lower the risk of death from bladder cancer.

Finasteride may affect brain chemistry and behavior, offering potential for treating certain mental health conditions.

The ABHRS held a test in Capri, Italy.

The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

FT-Raman spectroscopy is effective for identifying drug polymorphs, ensuring quality and stability.

Patients with rheumatoid arthritis using tofacitinib had more serious side effects than those with alopecia areata.

Oral 5-alpha reductase inhibitors do not increase breast cancer or benign breast disorder risk in women.

Compound 4 is a promising treatment for hair loss with low toxicity.

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

The gene LRRC15 is more active in balding areas of the scalp compared to non-balding areas.

Finasteride use linked to increased risk of sexual dysfunction, especially in younger people.

Runx1 helps control the KAP5 gene in human hair follicles.

A woman thought to have rosacea was actually suffering from Frontal Fibrosing Alopecia, a hair loss condition. Despite treatment, her condition didn't change, showing the importance of accurate early diagnosis.

An 8-year-old boy with Recklinghausen's Disease shows various symptoms and is from a family with close genetic ties.

New method accurately measures finasteride in tablets and bulk.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

The document concludes that various topical treatments show promise for skin conditions like atopic dermatitis, psoriasis, and hair loss.

A new tool helps study hair follicle cells to develop better treatments for hair disorders.

Ritlecitinib works well and is safe for treating alopecia areata.

The method effectively detects banned substances in urine for sports antidoping.

The NF-κB effector p65/RelA activates hair keratin genes, aiding hair formation.

miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.