13 citations
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December 2012 in “Cells” Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
160 citations
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January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
17 citations
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January 1997 in “Cell and Tissue Research” Scientists developed a method to grow human fetal skin and digits in a lab for 3-4 weeks, which could help study skin features and understand genetic interactions in tissue formation.
Researchers made a mouse model with curly hair and hair loss by editing a gene.
87 citations
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July 2009 in “Journal of Cell Science” Deleting the CDSN gene causes severe skin and hair problems, leading to death.
67 citations
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August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
1 citations
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January 2022 in “Stem cell biology and regenerative medicine” New methods to test hair growth treatments have been developed.
91 citations
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December 2000 in “The journal of cell biology/The Journal of cell biology” Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.
471 citations
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October 2012 in “Cellular and Molecular Life Sciences” Understanding developmental pathways can improve wound healing treatments.
56 citations
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January 1970 in “Cell and Tissue Research”
24 citations
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January 1993 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, works better for women, and requires consistent use.
11 citations
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January 2018 in “Acta dermato-venereologica” Researchers found specific genes in the part of hair follicles that could help treat hair disorders.
75 citations
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October 2010 in “Mammalian genome” Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.
191 citations
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November 1959 in “Annals of the New York Academy of Sciences” Hair and wool have complex microscopic structures with microfibrils and varying cystine content.
November 2024 in “Benha Journal of Applied Sciences” Reduced alpha smooth muscle actin may cause hair loss in androgenetic alopecia.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
6 citations
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May 2011 in “Pharmacognosy Journal” Many products for hair re-growth exist, but a perfect treatment without side effects has not yet been found.
27 citations
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November 2005 in “Archives of Dermatological Research” Choosing hair follicles at the same growth stage leads to more consistent hair growth experiments.
23 citations
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June 2010 in “Journal of Investigative Dermatology” A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.
8 citations
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October 1988 in “Clinics in dermatology” The best animal model for studying male-pattern baldness is the stumptailed macaque, not rats or mice.
The document discusses how traditional Chinese medicine extracts may affect hair growth in animals but lacks detailed results.
62 citations
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July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
1 citations
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October 2014 in “Skin Pharmacology and Physiology” People with alopecia areata have higher levels of osteopontin, which might be important in the disease's development, but this doesn't relate to how severe the disease is.
194 citations
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May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
1 citations
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December 2011 Marine-derived ingredients show potential for hair health but need more human trials to confirm effectiveness.
January 1989 in “Clinical and Experimental Dermatology” The symposium concluded that hair growth involves complex processes, including the hair follicle life cycle, the role of the dermal papilla, hair strength, pigmentation, and the impact of diseases and treatments like minoxidil on hair and skin.
120 citations
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November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
98 citations
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June 2008 in “Human mutation” A genetic change in the EDAR gene causes the unique hair traits found in East Asians.
97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
59 citations
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February 1998 in “Chemico-Biological Interactions” Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.