384 citations
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June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
286 citations
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April 2009 in “The journal of neuroscience/The Journal of neuroscience” TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
251 citations
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October 2014 in “The Journal of Clinical Endocrinology & Metabolism” The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
243 citations
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October 2003 in “Developmental biology” Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.
239 citations
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July 2002 in “Clinical and Experimental Dermatology” Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.
205 citations
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July 2009 in “Journal of Dermatological Science” Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
178 citations
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August 2016 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
152 citations
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January 2004 in “Current anthropology” Humans lost body hair relatively recently in evolution.
140 citations
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August 2011 in “Biomaterials” Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
122 citations
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May 2010 in “Plant Physiology” Different PIN proteins affect plant root hair growth by changing how auxin is transported.
112 citations
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November 2023 in “Nano-Micro Letters” Nanozymes show promise for effective and safe cancer treatment.
112 citations
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May 2019 in “Pharmacological Research” Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.
104 citations
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January 2005 in “Climacteric” Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.
104 citations
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November 1978 in “JAMA” The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.
97 citations
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October 2019 in “Journal of Translational Medicine” A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.
90 citations
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May 1972 in “Clinical Pharmacology & Therapeutics” Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.
86 citations
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June 2017 in “Anais Brasileiros de Dermatologia” Antioxidants can benefit skin health but should be used carefully to avoid negative effects.
78 citations
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August 2012 in “Human molecular genetics online/Human molecular genetics” A new gene, JMJD1C, may affect testosterone levels in men.
76 citations
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January 2019 in “Nanoscale” Created material boosts hair growth and kills bacteria for wound healing.
72 citations
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December 2009 in “Organic and Biomolecular Chemistry” Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.
68 citations
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March 1965 in “The BMJ” Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
65 citations
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May 2010 in “Current Women's Health Reviews” Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
58 citations
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March 1985 in “Journal of The American Academy of Dermatology” The document concludes that electrolysis and thermolysis can permanently remove hair but calls for better regulation to ensure safety, and notes a possibility of hair regrowth and rare complications.
47 citations
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September 2023 in “Pharmacological Reports” Vitamins A, B3, C, D, and E can improve skin health and immunity.
47 citations
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March 2017 in “Materials Science and Engineering: C” Human amniotic membrane helps heal skin wounds faster and with less scarring.
47 citations
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October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
47 citations
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September 2013 in “Aaps Pharmscitech” Improved hair loss treatment using special particles and surfactants.
47 citations
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October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
46 citations
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January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
45 citations
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January 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.