3 citations
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November 2015 in “Journal of Investigative Dermatology” Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
May 2025 in “Journal of Traditional Chinese Medical Sciences” Stellera chamaejasme L. extract promotes hair growth by activating hair growth genes.
June 2019 in “International journal of dermatology and venereology” The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
4 citations
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January 2012 in “Medical Hypotheses” Finasteride may improve stem cell therapy for heart attacks by increasing cell survival.
117 citations
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April 2008 in “Developmental biology” Ectodysplasin inhibits Wnt signaling to help form hair follicles.
66 citations
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July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
66 citations
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February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
56 citations
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May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
29 citations
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December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
13 citations
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August 2021 in “Frontiers in Bioengineering and Biotechnology” Exosomes from fat stem cells can reduce fat cell formation.
Wnt-activating drugs generally do not increase cancer risk.
October 2021 in “Scholarworks (University of Massachusetts Amherst)” FERONIA is crucial for plant growth, pollen tube reception, and sugar signaling.
21 citations
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February 2017 in “PLoS ONE” RhoA helps skin stem cells grow, aiding wound healing.
489 citations
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November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
35 citations
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May 2015 in “Thrombosis Research” Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
349 citations
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January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
15 citations
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November 2023 in “Immunity & ageing” TLR4 is important in aging-related diseases and could be a new treatment target.
1066 citations
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March 2010 in “Nature Reviews Molecular Cell Biology” MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
127 citations
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January 2008 in “PloS one” Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.
91 citations
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July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
88 citations
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January 2004 in “Journal of Neuroscience” Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.
72 citations
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October 2009 in “The FASEB journal” TRH stimulates human hair growth and extends the hair growth phase.
44 citations
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June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
40 citations
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April 2014 in “Genes & Development” Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
39 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
32 citations
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August 2016 in “Science Signaling” Alopecia areata patients show unique protein activity patterns, suggesting imbalanced signaling pathways.
29 citations
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February 2011 in “PloS one” Astressin-B can reverse and prevent hair loss in stressed mice.
29 citations
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December 2005 in “BioEssays” Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
22 citations
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August 2006 in “Critical Reviews in Plant Sciences” The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.
16 citations
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August 2022 in “Nature Communications” ROR2 is essential for hair follicle stem cell renewal and maintenance.