20 citations
,
December 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.
13 citations
,
January 2014 in “Journal of Investigative Dermatology” The laser comb did not improve hair regrowth in mice with alopecia areata.
1 citations
,
April 2018 in “Journal of Investigative Dermatology” Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.
October 2023 in “Regular and Young Investigator Award Abstracts” Baricitinib treatment helped reduce hair loss symptoms in mice by decreasing inflammation-related immune cells.
8 citations
,
March 1994 in “The American Journal of Cosmetic Surgery” The Total Excision Techniques improve hair transplant results by increasing grafts by at least 50% and reducing scarring.
5 citations
,
September 2005 in “Dermatologic Surgery” Using a polarized LED magnifier during hair transplants eases recipient site creation and reduces eye strain but doesn't improve graft creation or placement.
1 citations
,
September 2016 in “Indian Journal of Plastic Surgery” The new hair follicle harvesting technique improves hair transplant results and makes the procedure quicker and easier to learn.
1 citations
,
March 2006 in “Dermatologic Surgery” Using a polarized LED magnifier during hair transplants makes creating recipient sites easier and may increase hair density.
11 citations
,
August 2010 in “Journal of Dermatology” Hair transplantation can effectively treat stable eyebrow hair loss in alopecia areata patients.
391 citations
,
January 2010 in “Journal of The American Academy of Dermatology” Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
191 citations
,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
184 citations
,
February 2015 in “EBioMedicine” A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.
131 citations
,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
85 citations
,
October 2012 in “Dermatologic Clinics” Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.
82 citations
,
March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
64 citations
,
July 2016 in “Journal of Immunology” Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
60 citations
,
September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
40 citations
,
August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
30 citations
,
December 2001 in “Experimental dermatology” Gonadal hormones significantly affect the severity of alopecia areata in mice.
29 citations
,
June 2013 in “Journal of the Saudi Society of Dermatology & Dermatologic Surgery” Alopecia areata is an autoimmune hair loss condition treated with corticosteroids, and histologic confirmation is the best diagnosis method.
24 citations
,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
19 citations
,
January 2018 in “Acta dermato-venereologica” People with alopecia areata have higher levels of a heart disease marker than those without hair loss.
17 citations
,
June 2016 in “Croatian Medical Journal” Patients with chronic graft-versus-host disease often have skin problems like vitiligo and alopecia areata.
16 citations
,
May 2011 in “Dermatologic therapy” Effective treatments for severe alopecia areata are still lacking.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
14 citations
,
January 2006 in “Australasian journal of dermatology” Alopecia areata can look like frontal fibrosing alopecia, making diagnosis hard.
11 citations
,
May 2009 in “Actas Dermo-Sifiliográficas” Some treatments can help hair regrowth in alopecia areata, but none offer a cure, and effectiveness varies.
5 citations
,
June 1994 in “Journal of Cutaneous Pathology” No CD44 in alopecia areata, present in normal and androgenetic alopecia.
4 citations
,
May 2019 in “Journal of The European Academy of Dermatology and Venereology” Hair loss treatment caused more hair loss in a man.
4 citations
,
November 2023 in “Frontiers in immunology” New treatments targeting T-cell pathways are needed for better alopecia areata management.