research Fibroblast heterogeneity and tertiary lymphoid tissues in the kidney
Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
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research Lactoferrin promotes hair growth in mice and increases dermal papilla cell proliferation through Erk/Akt and Wnt signaling pathways
Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.
research AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research Safe Selection of Genetically Manipulated Human Primary Keratinocytes with Very High Growth Potential Using CD24
Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.
research Learning from nudity: lessons from the nude phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Establishment of an immortalized mouse dermal papilla cell strain with optimized culture strategy
Researchers created a long-lasting mouse skin cell strain that may help with hair growth research and treatments.
research 1465 Optimization/characterization of a Focal Dermal Hypoplasia mouse model to test potential treatments
Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs
ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
research Towards a molecular understanding of hair loss and its treatment
Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
research Exosomes for repair, regeneration and rejuvenation
Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
research Successive Release of Tissue Inhibitors of Metalloproteinase-1 Through Graphene Oxide-Based Delivery System Can Promote Skin Regeneration
Graphene oxide helps deliver a skin healing agent over time, improving skin and hair follicle regeneration.
research Molecular principles of hair follicle induction and morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Transcriptome Analysis of Improved Wool Production in Skin-Specific Transgenic Sheep Overexpressing Ovine β-Catenin
Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.
research CCN2 modulates hair follicle cycling in mice
The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
research Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions
The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
research The use of diphencyprone in dermatology: A retospective audit
Diphencyprone treatment protocols could be simplified as no harm occurred despite not fully following them.
research Effect of finasteride on ovulation induction in nonresponder (hyperandrogenic) polycystic ovary syndrome (PCOS) women
Finasteride helps induce ovulation in nonresponder PCOS women.
research Chemotherapy-induced alopecia
Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.
research Genetic basis of skin appendage development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures
The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
research Genetically-manipulated adult stem cells as therapeutic agents and gene delivery vehicle for wound repair and regeneration
Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
research Dermal Papilla Cells Serially Cultured with Wnt-10b Sustain their Hair Follicle Induction Activity after Transplantation into Nude Mice
Cells treated with Wnt-10b can grow hair after being transplanted into mice.
research In vivo monitoring of hair cycle stages via bioluminescence imaging of hair follicle NG2 cells
Bioluminescence imaging can track hair follicle cells and help study hair regrowth.
research Enhancing diabetic wound healing: advances in electrospun scaffolds from pathogenesis to therapeutic applications
Electrospun scaffolds can improve healing in diabetic wounds.
research Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture
Mechanical forces are crucial for shaping cells and forming tissues during development.
research Hoxc13 polyglycine repeat gain-of-function drives mammalian integument evolution by altering targeted genes and interactions
The polyG fragment in Hoxc13 protein helps evolve mammalian skin and hair by enhancing gene interactions.
research Activin A-induced signalling controls hair follicle neogenesis
Activin A is important for creating new hair follicles.
research MEF/KSF‑conditioned culture medium: An effective method forin vitroculture of mouse dermal papilla cells with osteogenic differentiation potential
MEF/KSF-conditioned medium effectively grows mouse hair follicle stem cells with bone-forming potential.
research Skin regeneration with conical and hair follicle structure of deep second-degree scalding injuries via combined expression of the EPO receptor and beta common receptor by local subcutaneous injection of nanosized rhEPO
Local injections of nanosized rhEPO can speed up skin healing and improve quality after deep second-degree burns.
research Rethinking regeneration: empowerment of stem cells by inflammation
Inflammation helps stem cells repair tissue by directing their behavior.