research Reversible decreases of fertility in male Sprague-Dawley rats treated orally with finasteride, a 5α-reductase inhibitor
Finasteride temporarily lowers male rat fertility without affecting libido.
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research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
research Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites
The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
research Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment
Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
research Inhibition of steroid 5 alpha-reductase with finasteride: sleep-related erections, potency, and libido in healthy men.
Finasteride doesn't affect erections much, but may decrease libido in men.
research Age-Related Changes in Female Scalp Dermal Sheath and Dermal Fibroblasts: How the Hair Follicle Environment Impacts Hair Aging
Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.
research Polycystic Ovary Syndrome
Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.
research Inhibitory Effects of Serenoa repens on the Kinetic of Pig Prostatic Microsomal 5α-Reductase Activity
Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.
research Hairline Lowering Surgery With Bone Tunneling Suture Fixation: Effectiveness and Safety in 91 Patients
The hairline lowering surgery with bone tunneling suture fixation is safe and effective, with high patient satisfaction.
research Influence of Postoperative Finasteride Therapy on Recurrence of Gynecomastia After Mastectomy in Men Taking Finasteride for Alopecia
Finasteride may not affect gynecomastia recurrence after mastectomy.
research Hair Restoration: Looking Beyond Minoxidil, Finasteride and Hair Transplantation
Need better hair loss treatments beyond minoxidil, finasteride, and transplants.
research A Teenage Girl with Unexpected Pubertal Changes
The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.
research FEATURES
Pharmacists play a key role in helping patients use over-the-counter products correctly, including those for hair regrowth and smoking cessation.
research Breaking the ‘rule-of-five’ to access bridged bicyclic heteroaromatic bioisosteres
A new method creates unique chemical structures that could improve drug discovery.
research EFFECT OF JALAUKAVACHARANA IN KHALITYA (HAIRFALL): A CASE REPORT
Leech therapy improved hair loss in a patient.
research Updates in Treatment for Androgenetic Alopecia
New treatments for hair loss include low-dose oral minoxidil, light therapy, and innovative therapies targeting hair growth mechanisms.
research “Acute Pancreatitis Following Finasteride Toxicity: A Rare Case Report"
Finasteride overdose can cause acute pancreatitis.
research Analysis of androgen receptor expression and activity in the mouse brain
Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
research MZ Cat Eye Lifting: A New Cosmetic Procedure for Brow Lifting
Choose the best brow lift method based on patient needs and goals.
research Effective Management of Hypothyroidism by Using Ayurvedic Interventions: A Case Report
Ayurvedic treatment improved hypothyroidism in a 30-year-old man.
research Gender Differences in Facial Rejuvenation
Men and women need different facial rejuvenation treatments due to distinct aging processes and anatomical differences.
research Hair Restoration: Looking Beyond Minoxidil, Finasteride and Hair TransplantationSonthalia*
The document concludes that current hair loss treatments have limitations and suggests researching new treatments targeting different factors of hair loss.
research Complications of Rhytidectomy
Face-lifts can lead to complications like bleeding, nerve injury, skin death, hair loss, and rare infections, with careful surgery reducing risks.
research Facial Hidradenitis Suppurativa in a 28-Year-Old Male Responding to Finasteride
Finasteride helped treat a 28-year-old's facial skin condition.
research Alopecia androgenética e seus tratamentos alternativos: uma revisão de literatura
Individualized treatment is crucial for managing hair loss and its effects.
research Pharmacological Approaches in Managing Symptomatic Relief of Benign Prostatic Hyperplasia: A Comprehensive Review
Tadalafil is effective for treating urinary symptoms in men with BPH.
research Adverse Side Effects of 5α‐Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients
Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
research The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride
Dutasteride more effective for hair growth, but has more side effects than finasteride.
research Summary of the Recommendations on Sexual Dysfunctions in Women
Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.
research Androgenetic Alopecia: An Evidence-Based Treatment Update
Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.