June 2025 in “General medicine and Clinical Practice” Lifestyle changes improve symptoms and fertility in hyper-androgenic women.
April 2019 in “Journal of Investigative Dermatology” Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.
29 citations
,
July 2009 in “BJU international” Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
April 2020 in “Journal of the Endocrine Society” A rare ovarian tumor caused high male hormone levels, but surgery fixed it.
16 citations
,
December 2010 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Normal levels for certain hormones in Chinese women of reproductive age were identified.
1 citations
,
January 2021 in “Prague medical report” Men might have a version of the female disease, polycystic ovarian syndrome, shown by changes in hormone levels and early baldness, but more research is needed to fully understand it.
117 citations
,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
2 citations
,
October 2015 in “Obstetrics and gynaecology cases - reviews” Removing both ovaries may better treat increased male hormone levels and related symptoms in postmenopausal women when hormone therapy doesn't work.
June 2025 in “Skin Research and Technology”
31 citations
,
January 2018 in “Pediatric annals” Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
December 2020 in “Research Square (Research Square)” Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.
January 2021 in “Deep Blue (University of Michigan)” Androgen receptors in the brain affect metabolism and reproduction differently in males and females, and may help manage PCOS symptoms in females.
29 citations
,
February 2018 in “Genetics research international” Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.
42 citations
,
October 2004 in “Experimental and Clinical Endocrinology & Diabetes” The main cause of excessive hair growth in Turkish women is Polycystic ovary syndrome, but in about one fifth of cases, the reason for high male hormone levels is unknown.
December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may help treat hidradenitis suppurativa.
17 citations
,
April 2010 in “Archives of Gynecology and Obstetrics” Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.
January 2016 in “Archivio italiano di urologia, andrologia” The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
8 citations
,
January 1991 in “European Urology” Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
21 citations
,
May 2001 in “PubMed” Androgen hormones affect hair growth and oil production, influencing conditions like hair loss and acne.
31 citations
,
February 1997 in “The Journal of Clinical Endocrinology and Metabolism” People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.
38 citations
,
October 1996 in “Dermatologic Clinics” Certain hormone treatments can improve acne and related conditions in women.
4 citations
,
November 2018 in “Endocrinology, Diabetes & Metabolism Case Reports” GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.
49 citations
,
January 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” RU 58841 may treat acne, hair loss, and excessive hair growth.
November 2007 in “Data Archiving and Networked Services (DANS)” Androgen receptors play a key role in male development and prostate cancer, with treatments targeting androgen action.
Anti-androgens can help treat tough skin conditions like severe acne and excessive hair growth.
23 citations
,
May 1984 in “Journal of the American Geriatrics Society” Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.
1 citations
,
September 2023 in “JCEM case reports” GnRH analogues are effective for diagnosing and treating female androgen excess, offering a non-surgical option.
100 citations
,
September 2017 in “Molecular and Cellular Endocrinology” Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
May 2025 in “International Journal of Nursing Education and Research” Hyperandrogenism causes significant physical and emotional challenges, needing better understanding and support.
47 citations
,
August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.