77 citations
,
August 2025 in “Signal Transduction and Targeted Therapy” Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
77 citations
,
July 2012 in “Journal of Investigative Dermatology” Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.
67 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.
58 citations
,
March 2020 in “Scientific Reports” EGFR-TKIs can cause significant skin, nail, and organ side effects.
55 citations
,
October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
50 citations
,
September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
49 citations
,
January 1980 in “Journal of Cardiovascular Pharmacology” Minoxidil doesn't increase pericardial disorder risk, but may cause fluid accumulation.
36 citations
,
May 2011 in “Dermatologic therapy” No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.
33 citations
,
January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
33 citations
,
August 2006 in “Journal der Deutschen Dermatologischen Gesellschaft” Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.
29 citations
,
December 2005 in “BioEssays” Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
25 citations
,
April 2015 in “Journal of Investigative Dermatology” GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.
23 citations
,
December 2004 in “Seminars in oncology” Liposomal anthracyclines are effective and safer for treating multiple myeloma, especially in elderly patients.
21 citations
,
January 2013 in “Annals of dermatology/Annals of Dermatology” The combination of cyclosporine and PUVA might help treat severe alopecia areata.
21 citations
,
April 2011 in “Epilepsia” The drug combination significantly reduced epileptic drop attacks in patients.
20 citations
,
February 1977 in “Circulation” Minoxidil lowers blood pressure and increases heart efficiency, but may raise lung artery pressure in some people.
17 citations
,
January 2010 in “Acta Dermato Venereologica” EGFR inhibitors can cause yellowish skin eruptions.
16 citations
,
May 2011 in “Dermatologic therapy” Effective treatments for severe alopecia areata are still lacking.
15 citations
,
April 2016 in “Eye” Finasteride effectively treats central serous chorioretinopathy.
12 citations
,
August 2016 in “Current opinion in genetics & development” Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
12 citations
,
September 2002 in “Epilepsia” Monitoring new epilepsy drugs after they're sold is crucial to find rare and long-term side effects that initial tests might miss.
11 citations
,
April 2009 in “Pharmacotherapy” Minoxidil can cause deadly skin reaction; monitor patients closely.
11 citations
,
May 2010 in “Journal of the South African Veterinary Association” Mycophenolate mofetil helped reduce steroid use in treating a dog's autoimmune skin disease.
7 citations
,
September 2013 in “Current Dermatology Reports” Some skin medications are safe for pregnant women, but others pose risks or should not be used.
6 citations
,
September 1988 in “Drug intelligence & clinical pharmacy” Minoxidil caused a severe rash in a patient, which improved after stopping the drug.
3 citations
,
October 2010 in “Epilepsy Currents” Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
2 citations
,
July 2014 in “Irish Journal of Medical Science” The meeting discussed medical findings, including benefits of certain treatments for cancer and heart conditions, and highlighted issues like poor adherence to preventive measures and skill gaps among interns.
1 citations
,
January 2023 in “Research Square (Research Square)” A woman's vitiligo improved with tofacitinib treatment, and her skin color remained even after stopping the medication, but there are concerns about cancer risk.
1 citations
,
February 2022 in “Veterinární Medicína” A cat fully recovered from minoxidil poisoning with specific treatments.
1 citations
,
November 2018 in “Therapeutic Delivery” New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.