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Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.

Applying estradiol to skin causes local changes but not cancer.

Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Estrogen treatments can cause unwanted effects in men and should be used cautiously.

A new method effectively predicts estrogen-related health effects for early screening.

17β-estradiol lowers polyamine oxidase levels in breast cancer cells through estrogen receptor 2.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

New therapies are needed to reduce the burden of alopecia areata.

New guidelines and referral pathways for skin conditions aim to improve care and referrals in Pakistan.

NexGard® and Frontline Combo® are both 100% effective at eliminating lice in dogs.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

The new method showed that endometriotic tissue has lower estrogen receptor levels but similar progesterone levels compared to normal endometrium, with both following a similar cycle.

Androgen receptors in the brain affect metabolism and reproduction differently in males and females, and may help manage PCOS symptoms in females.

Estrogen and its receptors play a key role in hair growth, with differences between males and females.

Estrogens and androgens are crucial for male fertility.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

17α-estradiol extends lifespan and improves metabolism in male mice through the estrogen receptor α.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Estrogen alone may effectively suppress testosterone in some transfeminine individuals.

Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

Estrogen alone can lower testosterone in some transfeminine people.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.

Fetal ovaries produce different hormones than adult ovaries, and endocrine-disrupting chemicals may affect this process.

The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.

Reducing 5α-reductase activity helps endometrial cells differentiate, aiding pregnancy.

Blocking androgen receptors early in life increases estrogen levels and reduces sexual motivation in male rats.

17b-Estradiol in skin affects hair growth and tumor promotion.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.