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The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

FCER1A and RGS1 may help diagnose and treat systemic lupus erythematosus.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

OR2AT4 helps reduce aging and cell damage in human skin cells.

Glycine likely affects dendrites connected to hair follicle terminals in rats.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

The study developed methods to measure biomarkers in mice and found differences in hormone levels linked to gut microbiota diversity and stress response.

TRα and CRABPII genes change their activity levels during goat fetal skin development.

Gene expression affects fur development in rex rabbits.

Laminin-511 is involved in psoriasis development and can be regulated by cannabinoid receptor type 1.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

Calcium reduces involucrin in rat hair bulbs but doesn't affect filaggrin and Kdap.

LncRNAs play a crucial role in muscle regulation and could help develop treatments for Duchenne muscular dystrophy.

TRPV3 channels are involved in skin processes and are affected by shear stress, influencing itch and mechanotransduction.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

ASLAN004 was safe and well-tolerated, supporting further development for treating certain diseases.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

The frizzy mouse and hairless rat mutations are due to changes in the Prss8 gene.

Dopaminergic neurons in the gut have distinct subtypes, some releasing both dopamine and acetylcholine.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

Different sPLA2 enzymes have unique roles in phospholipid metabolism and biological processes.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.

Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.