research Polycystic ovary syndrome: diagnosis and management of related infertility
Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.
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research Early androgen activity after birth determines the hypothalamic expression of androgen and estrogen receptors in adulthood in female but not in male rats
Early androgen exposure affects hormone receptor expression in adult female rats' brains, but not in males.
research 231 Novel protocol for the invitro maintenance and expansion of adult epidermal LGR5+ stem cells
A new method helps grow skin stem cells better, which could improve skin grafts for burn victims.
research Ovarian sex steroid receptors and sex hormones in androgenized rats
High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.
research Metformin treatment of polycystic ovary syndrome improves health-related quality-of-life, emotional distress and sexuality
Metformin improves quality of life, emotional health, and sex life in women with polycystic ovary syndrome.
research PCOS and Depression: Common Links and Potential Targets
Women with PCOS often experience depression and anxiety, affecting their quality of life.
research Cosmetic side effects of antiepileptic drugs in adults with epilepsy
Some antiepileptic drugs can cause weight gain and hair loss, especially in women.
research Hair corticosterone measurement in mouse models of type 1 and type 2 diabetes mellitus
New hair growth corticosterone levels are higher in diabetic mice, indicating long-term stress.
research Attenuating 5α-pregnane-3α-ol-20-one formation in the hippocampus of female rats increases pentylenetetrazole-induced seizures
Reducing 3α,5α-THP in the hippocampus increases seizures in female rats.
research The effects of statins on hyperandrogenism in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials
Statins can reduce androgen levels and improve symptoms in women with PCOS.
research Polycystic ovary syndrome: Criteria, phenotypes, race and ethnicity
PCOS diagnosis and treatment should consider race and ethnicity for accuracy.
research New hyaluronan-based biomatrix for 3-D follicle culture yields functionally competent oocytes
A new hyaluronan-based biomatrix successfully supports the growth of mouse ovarian follicles, producing healthy eggs.
research The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial
Magnesium supplements improved quality of life for women with polycystic ovary syndrome, but didn't help with acne, hair loss, or abnormal bleeding.
research Microglia: sculptors of the polycystic ovary syndrome (PCOS)-like brain?
Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.
research Modern approaches to the diagnosis and treatment of polycystic ovary syndrome in adolescence
New methods for identifying and managing polycystic ovary syndrome in teenagers are improving.
research Androgen insufficiency in women: diagnostic and therapeutic implications
Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
research Null Mutation of 5α-Reductase Type I Gene Alters Ethanol Consumption Patterns in a Sex-Dependent Manner
research Patient characteristics associated with symptoms of anxiety, depression, and reduced body appreciation in women with polycystic ovary syndrome
Women with PCOS often face anxiety, depression, and low body appreciation, especially if they have alopecia, obesity, or a history of mental health issues.
research Erectile dysfunction: Is platelet-rich plasma the new frontier for treatment in patients with erectile dysfunction? A review of the existing evidence
Platelet-rich plasma shows promise for treating erectile dysfunction, but more research is needed.
research A review of hyperandrogenism state in polycystic ovarian syndrome
Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.
research Outcome of long-term treatment with the 5α-reductase inhibitor finasteride in idiopathic hirsutism: clinical and hormonal effects during a 1-year course of therapy and 1-year follow-up
Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Endocrine care of transpeople part I. A review of cross-sex hormonal treatments, outcomes and adverse effects in transmen
Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
research Cardiovascular risk in women with premature ovarian insufficiency compared to premenopausal women at middle age
Women with premature ovarian insufficiency have a worse cardiovascular risk profile than premenopausal women.
research Sexual dysfunction, including hypoactive sexual desire disorder: Diagnosis and treatment recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research Managing hair loss in midlife women
Effective treatment for midlife women's hair loss is limited, with 5% minoxidil foam being the only proven option for the most common type.
research Seasonality,.Climatic.Unpredictability,.Food. Deprivation,.and.Polycystic.Ovary.Syndrome
PCOS may have evolved as an advantage in past environments with food scarcity.
research Aging in the Male Face: Intrinsic and Extrinsic Factors
Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.
research Mesotherapy as a Promising Alternative to Minoxidil for Androgenetic Alopecia: A Systematic Review
Mesotherapy is a promising alternative to minoxidil for hair loss with mild side effects.
research What is the best treatment for female pattern hair loss?
Topical minoxidil 1% and 2% are twice as effective as placebo for female pattern hair loss.