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Donor lymphocyte infusions effectively treated leukemia relapse but caused vitiligo and alopecia areata.

A rare case of a woman having both lichen planus pigmentosus and classic lichen planopilaris at the same time.

A child with rough nails also had hair loss and allergies.

A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Oral contraceptives with desogestrel and drospirenone improve PCOS symptoms.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

Some common medications can harm male fertility, but many effects can be reversed.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Cancer development is like natural selection, involving mutated cells and environmental factors.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Alopecia in captive rhesus macaques is affected by season, sex, age, housing, and stress, with complex links between stress hormones and hair loss.