19 citations
,
July 2013 in “The obstetrician & gynaecologist” The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
18 citations
,
May 2014 in “Menopause” A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.
16 citations
,
May 2020 in “Frontiers in pharmacology” Minoxidil can stop the growth of ovarian cancer cells without harming the heart.
15 citations
,
August 2016 in “Current Urology Reports” Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.
14 citations
,
January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
14 citations
,
February 2016 in “Journal of Obstetrics and Gynaecology Research” Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.
12 citations
,
January 2007 in “Acta dermato-venereologica” Europe needs a clear system to watch over cosmetics for safety and to make sure product claims are true.
11 citations
,
August 2019 in “The Journal of Sexual Medicine” Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.
11 citations
,
February 2018 in “Amino acids” Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
11 citations
,
November 2009 in “Sports Medicine” Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.
11 citations
,
August 2009 in “Expert Opinion on Drug Discovery” We need better ways to test and understand SARMs to make safer and more effective treatments.
10 citations
,
June 2010 in “Expert Opinion on Drug Metabolism & Toxicology” Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
10 citations
,
April 1995 in “Animal Science/Animal science” Melatonin implants can change the seasonal prolactin levels and hair growth in adult cashmere goats but not in juveniles, and don't delay spring moult for better fiber harvesting.
9 citations
,
March 2019 in “European Journal of Sport Science” New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
9 citations
,
November 2015 in “Gynecological Endocrinology” Different types of PCOS in Chinese Han women show varying levels of male hormone and metabolic issues.
9 citations
,
September 2014 in “Cancer Epidemiology, Biomarkers & Prevention” Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.
8 citations
,
January 2017 in “Fertility and Sterility” Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.
8 citations
,
March 2010 in “Gynecological Endocrinology” Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.
7 citations
,
October 2020 in “Journal of Clinical Medicine” Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.
7 citations
,
October 2019 in “Evidence-based Complementary and Alternative Medicine” Chinese medicine may help hair growth and reduce hair loss in androgenetic alopecia.
7 citations
,
January 2018 in “Australian Prescriber” Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.
6 citations
,
September 2012 in “Clinical Interventions in Aging” Honokiol might help reduce male skin aging by maintaining testosterone levels.
5 citations
,
June 2020 in “Journal of Endocrinological Investigation” Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.
4 citations
,
September 2024 in “BMC Cancer” Adding dutasteride to therapy may improve treatment for advanced salivary duct cancer.
4 citations
,
May 2019 in “Physiology & Behavior” Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.
3 citations
,
May 2025 in “Frontiers in Pharmacology” Vismodegib can cause muscle spasms, taste changes, hair loss, fatigue, weight loss, and possibly new issues like skin cancer, dehydration, and swallowing problems, needing close monitoring.
3 citations
,
September 2022 in “Frontiers in psychiatry” University students in Egypt experienced high stress during COVID-19's third wave, with negative coping mechanisms being more common.
3 citations
,
February 2021 in “Molecules” A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
2 citations
,
August 2023 in “Journal of Endocrinological Investigation” Excess maternal androgens can cause heart problems in offspring.