June 2026 in “Open Access Research Journal of Biology and Pharmacy” This study investigates potential multi-target drugs against Onchocerca volvulus, a major cause of blindness in developing regions. Using molecular docking simulations, 2,015 approved drugs were screened against glutamate S-transferase and prolyl tRNA synthetase. Bedaquiline and Telmisartan showed the strongest binding affinities, while Diosmin, Azelastine, and Adapalene were identified as promising multi-target drugs based on molecular dynamics. Other compounds like Drospirenone, Alectinib, Dutasteride, and Finasteride also showed potential. The study suggests repurposing these drugs could offer effective treatments for onchocerciasis, with further validation needed.
5 citations
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September 2011 in “Bioorganic & Medicinal Chemistry Letters” Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
September 2022 in “Zenodo (CERN European Organization for Nuclear Research)” 
January 1988 in “Inpharma (Balgowlah)” New retinoids are effective for various skin conditions and are being developed to have fewer side effects.
1 citations
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April 2010 in “OhioLink ETD Center (Ohio Library and Information Network)” Resveratrol works against cancer, and it's even better with vitamin C.
October 2025 in “Open Repository of the University of Porto (University of Porto)” 13 citations
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January 2017 in “Annals of dermatology/Annals of Dermatology” Simvastatin/ezetimibe may help some patients with severe alopecia areata regrow hair.
102 citations
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September 1977 in “The Lancet” Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.
5 citations
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January 1997 in “PubMed” 20 citations
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December 2021 in “Journal of the American Academy of Dermatology” Continuous treatment with ritlecitinib and brepocitinib is needed to maintain hair regrowth in alopecia areata.
March 2005 in “European Urology Supplements” Finasteride may reduce heart damage in rats.
August 2002 in “Inpharma Weekly” 
December 2021 in “Medicina estética” Serenoa repens may help treat hair loss but is less effective than common medications and needs more research to confirm its effectiveness.
![Activity of 17β-(N-Alkyl/Arylformamido) and 17β-[(N-Alkyl/Aryl) Alkyl/Arylamido]-4-Methyl-4-Aza-5α-Androstan-3-Ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear](/images/research/861159f1-7bd4-420c-a16b-4829458efe68/small/15592.jpg)
10 citations
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August 1998 in “Journal of Investigative Dermatology” The compounds tested could potentially treat hair loss and alopecia.
4 citations
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March 2022 in “Cosmetics” Nourella® effectively improves skin thickness and elasticity, reversing aging signs.
November 2009 in “Eclética Química” The conclusion cannot be provided as the document content is not available.
34 citations
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July 1993 in “PubMed” A medicine company has recalled a drug because it contained an unlisted blood pressure medication.
153 citations
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November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
July 2025 in “Derecho y cambio social.” Policosanol biorefining shows promise for heart health, needing better academic-industrial collaboration.
11 citations
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January 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
October 2020 in “Open Repository of the University of Porto (University of Porto)” 4 citations
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August 2023 in “Biomedicine & Pharmacotherapy” Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.
November 2023 in “Open Repository of the University of Porto (University of Porto)” 5 citations
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December 2011 in “Vox Sanguinis” Some blood donors on teratogenic drugs may have unsafe drug levels, suggesting a need for better deferral policies.
17 citations
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October 2013 in “Der Hautarzt” October 2022 in “Amplla Editora eBooks”