1 citations
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June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Fetal skin has unique immune cells different from adult skin.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Adipocytes can change into fibroblast-like cells to help with wound healing.
35 citations
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May 2012 in “Expert Opinion on Pharmacotherapy” The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
252 citations
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April 2009 in “Seminars in Cell & Developmental Biology” The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
238 citations
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March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
192 citations
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March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
191 citations
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May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
82 citations
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March 2016 in “Autoimmunity reviews” Animal models have helped understand hair loss from alopecia areata and find new treatments.
81 citations
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June 2014 in “Cold Spring Harbor perspectives in medicine” Skin has specialized touch receptors that can tell different sensations apart.
60 citations
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September 2015 in “Expert Review of Clinical Immunology” Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
60 citations
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June 1997 in “Journal of The American Academy of Dermatology” Apoptosis is crucial for healthy skin and treating skin diseases.
42 citations
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October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
35 citations
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May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
21 citations
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March 2018 in “Experimental Dermatology” The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
11 citations
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March 2020 in “Immunology” Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
10 citations
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November 2010 in “Pigment Cell & Melanoma Research” Only skin melanocytes, not other types, can color hair in mice.
4 citations
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November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
3 citations
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December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
2 citations
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April 2017 in “Asian Journal of Psychiatry” Valproic acid can cause hair loss when taken orally but may promote hair growth when applied topically.
April 2026 in “Frontiers in Immunology” Blocking the CXCL12–CXCR4 axis may help treat hair loss in alopecia.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” ILC1-like cells can cause alopecia areata by attacking hair follicles.
Live imaging helps us understand skin immune responses and develop treatments.
38 citations
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June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” Immune cells and plasma proteins are linked to hair loss, suggesting new treatment options.
April 2021 in “Sohag Medical Journal” Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
31 citations
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February 2014 in “Inflammation Research” Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.
October 2023 in “International Journal of Science and Research (IJSR)” Early diagnosis of GLPLS is crucial to prevent complications, but scarring alopecia is irreversible.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.