research Drug-associated gingival disorders: a retrospective pharmacovigilance assessment using disproportionality analysis
Certain medications can cause gum problems, so patients and healthcare providers should be aware and monitor oral health.
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research A meta-analysis of the effectiveness and safety of Sintilimab combined with chemotherapy in the trea tment of advanced non-small cell lung cancer
Sintilimab with chemotherapy improves survival and response in advanced lung cancer but increases some side effects.
research Assessment, diagnosis and treatment of a patient with hirsutism
A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.
research Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine
A new triple drug system using nanoparticles effectively targets breast tumors in 3D models.
research Emerging Strategies in Smart Nano-PROTAC for Stimuli-Responsive Protein Degradation and Precision Cancer Therapy
Smart nano-PROTACs improve cancer treatment by targeting proteins more precisely and reducing side effects.
research Intestinal Lymphatic Biology, Drug Delivery, and Therapeutics: Current Status and Future Directions
The intestinal lymphatic system is active and promising for targeted drug delivery and therapies.
research Modulating the Antioxidant Response for Better Oxidative Stress-Inducing Therapies: How to Take Advantage of Two Sides of the Same Medal?
Enhancing antioxidant responses can improve treatments for various diseases.
research Activation of cAMP Signaling in Response to α-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells
α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.
research Genetically engineered biomimetic ATP-responsive nanozyme for the treatment of cardiac fibrosis
A new engineered treatment shows promise in curing heart fibrosis.
research Evaluation of an eucalyptus oil containing topical drug delivery system for selected steroid hormones
The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
research Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
research The Cutaneous Inflammatory Response to Thermal Burn Injury in a Murine Model
Burn injuries in mice heal similarly to humans, with inflammation and cell changes normalizing over time.
research Structural Study of Polymorphs and Solvates of Finasteride
Different forms of hair loss drug can improve effectiveness.
research LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway
LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
research Gender Differences in Response to COVID-19 Infection and Vaccination
Men generally face more severe COVID-19 outcomes than women, partly due to hormonal differences.
research Turmeric Essential Oil Constituents as Potential Drug Candidates: A Comprehensive Overview of Their Individual Bioactivities
Turmeric essential oil compounds have potential as safe, effective drugs.
research Semifluorinated Alkanes as New Drug Carriers—An Overview of Potential Medical and Clinical Applications
Semifluorinated alkanes are promising for delivering drugs in various medical applications.
research Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma
Ozone and procaine boost the release of healing factors in platelet-rich plasma.
research Analysis of Adverse Drug Reactions in Pediatric Patients with Epilepsy: An Intensive Pharmacovigilance Study
Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.
research The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
Serine is vital for hair follicle stem cells to balance hair growth and skin repair.
research US Food and Drug Administration Warning Regarding Finasteride and Suicidal Ideation: What Should Urologists Know?
Urologists should screen for mental health issues before and during finasteride treatment.
research Recent advances in glycopeptide hydrogels: design, biological functions, and biomedical applications
Glycopeptide hydrogels are promising for tissue repair, drug delivery, and healing due to their multifunctional properties.
research Natural products reverse cancer multidrug resistance
Natural products can help overcome cancer drug resistance.
research Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment
A new method quickly creates controllable cell clusters for tissue engineering and drug testing.
research Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis
Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.
research Mimicking Senescence Factors to Characterize the Mechanisms Responsible for Hair Regression and Hair Loss: An In Vitro Study
TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.
research Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer
Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
research Quality evaluation of the Finasteride polymorphic forms I and II in capsules
Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.
research The ATP sensitive potassium channel (KATP) is a novel target for migraine drug development
Blocking the KATP channel may help treat migraines.
research A review for cell-based screening methods in drug discovery
Cell-based screening methods are useful and cost-effective for drug discovery but have pros and cons.