109 citations
,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
106 citations
,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
100 citations
,
September 2017 in “Molecular and Cellular Endocrinology” Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
99 citations
,
June 2005 in “Journal of Cosmetic Dermatology” Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.
98 citations
,
February 2007 in “Seminars in Cell & Developmental Biology” Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
94 citations
,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
92 citations
,
September 2019 in “ACS nano” A wearable device using electric stimulation can significantly improve hair growth.
86 citations
,
July 2020 in “International Journal of Molecular Sciences” Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
86 citations
,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
83 citations
,
January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
81 citations
,
June 2010 in “Journal of Dermatological Treatment” The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.
81 citations
,
January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
77 citations
,
July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
70 citations
,
February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
69 citations
,
April 2019 in “Biomedicines” PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.
68 citations
,
March 2018 in “Biomaterials” Tiny needles with valproic acid can effectively regrow hair.
67 citations
,
August 2013 in “International Journal of Cosmetic Science” Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
67 citations
,
May 2007 in “Journal of Cosmetic Dermatology” The herbal formulation promoted hair growth faster and more effectively than minoxidil in rats.
62 citations
,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
60 citations
,
December 2015 in “Lasers in Medical Science” Low-level laser therapy is safe and can increase hair growth for male and female pattern hair loss.
60 citations
,
December 2005 in “Biomedical Papers” Hair analysis can detect drug use but requires careful interpretation due to its complexity.
60 citations
,
January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Applying a specific inhibitor lightens skin and hair color.
59 citations
,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
59 citations
,
August 1998 in “International Journal of Dermatology” Genetics and hormones cause hair loss; finasteride treats it safely.
54 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
54 citations
,
June 1985 in “American Journal of Dermatopathology” Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
52 citations
,
May 2015 in “PLOS Genetics” miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.
52 citations
,
October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
52 citations
,
June 2009 in “Current Opinion in Endocrinology, Diabetes and Obesity” The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.