June 2025 in “Biomolecules” RORA affects hair follicle stem cells' structure and movement, potentially helping treat hair loss.
December 2024 in “Animals” RORA may help regulate hair growth by affecting hair follicle stem cells.
April 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Ezh2 controls skin development by balancing signals for dermal and epidermal growth.
Retinoids can cause skin issues and hair loss due to their effects on cell membranes.
October 2019 in “CRC Press eBooks” Retinoids can both cause and treat different hair disorders.
April 2016 in “Journal of Investigative Dermatology” Retinoids change the fat content in skin oil and reduce bacteria growth, helping to treat acne.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
June 2010 in “The Knowledge Bank (The Ohio State University)” Inhibiting retinoic acid activates WNT signaling, potentially aiding hair disorder and skin cancer treatments.
January 1988 in “Inpharma (Balgowlah)” New retinoids are effective for various skin conditions and are being developed to have fewer side effects.
Retinoids can help reduce keratin buildup in skin conditions.
April 1982 in “Journal of The American Academy of Dermatology” Retinoids help treat psoriasis effectively, but they can cause side effects and need more research on safe use with other treatments.
48 citations
,
March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Retinoic acid production and signaling in hair follicles are regulated by location and timing, affecting hair growth and cycling.
37 citations
,
June 1996 in “Journal of cellular physiology” Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.
32 citations
,
March 1988 in “International Journal of Dermatology” Retinoids can help treat skin disorders by improving the skin's outer layer.
29 citations
,
July 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzymes Aldh1a2 and Aldh1a3 are involved in making retinoic acid in hair follicles and have different roles in hair growth.
28 citations
,
August 1981 in “Journal of the American Academy of Dermatology” Retinoic acid is effective for treating eruptive vellus hair cysts.
26 citations
,
May 1991 in “Clinical and experimental dermatology” Oral etretinate improved hair length and reduced beading in monilethrix.
24 citations
,
July 1994 in “Journal of Investigative Dermatology” 20 citations
,
April 2019 in “BioMed Research International” Treatments with sunscreen and active ingredients can reduce skin hyperpigmentation by decreasing DNA methylation.
19 citations
,
August 1998 in “Journal of the American Academy of Dermatology” Hair loss can signal serious health issues, not just cosmetic concerns.
19 citations
,
October 1988 in “Clinics in dermatology” Retinoids might help hair grow and improve hair loss treatments.
18 citations
,
June 1993 in “Archives of Dermatological Research” Human hair follicles can be used to create skin-like tissue for wound healing and drug testing.
16 citations
,
November 1994 in “Developmental Biology” Retinoic acid causes gland formation instead of hair in mouse skin by altering epidermal and dermal interactions.
15 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Retinoids can change the hair growth cycle by extending the growth phase and shortening the rest phase.
14 citations
,
January 2011 in “The International Journal of Developmental Biology” Retinoic acid changes skin cells to mucosal cells with goblet cells, needing TG2/Gh, Gbx1, and TGF-beta.
10 citations
,
January 2004 in “Journal of Investigative Dermatology” Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.
7 citations
,
May 2010 in “Drug Delivery” Retinoic acid and DMSO improve gene delivery to mouse skin for potential hair and skin disease treatment.
4 citations
,
January 2016 in “Methods in molecular biology” Hair follicle stem cells can become nerve cells using specific treatments.
3 citations
,
August 2021 in “Nutrition research” Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.