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Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.

PAD enzymes play a key role in hair growth and structure.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.

Foreskin keratinocytes and SVK14 cells express certain cytochrome P450 enzymes, unlike hair follicle keratinocytes.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

Topical tretinoin may increase beard hair density.

PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.

AMPK activation may reduce melanoma risk in red-haired individuals.

Ritlecitinib was generally well tolerated in children with alopecia areata.

Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

Vitamin D receptor gene changes don't affect alopecia areata risk.

Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

Both HPSAM and PLS methods accurately measure minoxidil and tretinoin concentrations.

The Rotterdam Study investigates diseases in older adults and has produced many research findings.

Vitamin D receptor is crucial for hair growth, not vitamin D itself.

Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.

5α-reductase 2 is crucial for stress response in male rats.

Hair loss in Clouston's syndrome improved with minoxidil and tretinoin treatment.

Two siblings with a rare type of rickets and hair loss had low vitamin D levels, which is not typical for their condition.

α-Tocopheryl acetate is well absorbed through healthy skin.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Activated ras can protect kidney cells from a certain substance that causes cell death.

Repigmentation patterns in vitiligo depend on melanocyte source, lesion status, and therapy choice.