September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Intermittent isotretinoin can cause various skin, hair, and nail changes.
April 2019 in “Journal of Investigative Dermatology” Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
January 1994 in “Toxicological Sciences” Lower dosages of 2-(difluoromethyl)-dl-ornithine might reduce side effects, supporting further research.
September 2024 in “Health Problems of Civilization” Isotretinoin effectively treats severe acne but has significant side effects requiring careful monitoring.
1 citations
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June 2014 in “Journal of developmental biology” Retinoic acid helps change skin cells and is important for skin development and hair growth.
10 citations
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August 1998 in “Journal of Investigative Dermatology”
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April 1981 in “Clinical endocrinology” A girl with rickets and hair loss was found to have a rare condition where her body didn't respond to vitamin D treatment.
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July 1994 in “Journal of Investigative Dermatology” 151 citations
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June 2010 in “Endocrinology and metabolism clinics of North America” Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.
Teprotumumab for thyroid eye disease commonly causes fatigue, brittle nails, dry eyes, hair loss, muscle spasms, and dry mouth, with rare serious events like blood clots.
5 citations
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July 2019 in “Journal of Cutaneous Medicine and Surgery” Isotretinoin may cause hair loss, especially in women and young adults.
3 citations
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October 2019 in “CRC Press eBooks” Isotretinoin effectively treats severe acne but can cause significant side effects like dry skin and hair loss.
121 citations
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June 2010 in “Australasian Journal of Dermatology” Most people on isotretinoin had chapped lips, but only a few stopped the medicine due to side effects.
October 2019 in “International journal of research in dermatology” Misusing topical corticosteroids can cause skin darkening and other side effects.
December 2015 in “Journal of Psoriasis and Psoriatic Arthritis” A patient experienced long-lasting hair loss after using acitretin for psoriasis.
67 citations
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August 2004 in “Endocrinology” A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.
March 2019 in “Reactions Weekly” 98 citations
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May 2010 in “British Journal of Dermatology” Isotretinoin is effective for severe acne but requires careful monitoring for side effects, especially in women who could become pregnant.
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February 2018 in “Military medicine” A U.S. Naval fighter pilot suffered permanent vision loss in one eye due to recurrent central serous retinopathy.
15 citations
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March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
February 2022 in “International Journal of Research in Dermatology” Tretinoin alone is more effective than combined with microdermabrasion for long-term alopecia areata treatment.
1 citations
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January 2025 in “CPT Pharmacometrics & Systems Pharmacology” Ritlecitinib effectively regrows eyebrow and eyelash hair in alopecia areata, with 50 mg being the best dose.
March 2024 in “Ukraïnsʹkij žurnal dermatologìï, venerologìï, kosmetologìï” Topical retinoids are important for treating acne effectively and safely.
66 citations
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January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
4 citations
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January 2001 in “Archives of Biochemistry and Biophysics” Activated ras can protect kidney cells from a certain substance that causes cell death.
January 1978 in “Clin-Alert” A document listed serious side effects from various drugs, including deaths and diseases, emphasizing the importance of being aware of drug side effects.
RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.
8 citations
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April 2019 in “Dermatologic Therapy” Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.
1 citations
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July 2024 in “Cureus” Early recognition of methotrexate toxicity symptoms is crucial.
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December 2016 in “Hormone Research in Paediatrics” Tunisian children with hereditary vitamin D-resistant rickets showed improvement with calcium treatment, and new genetic mutations were identified.